3 citations
,
July 2025 in “International Journal of Biological Sciences” This review highlights that the RNA modification N6-methyladenosine (m6A) plays a crucial role in regulating wound healing and tissue remodeling, with dysregulation contributing to complications in chronic wounds, such as diabetic ulcers and burn injuries, through mechanisms like impaired angiogenesis and increased oxidative stress.
This review discusses lifestyle interventions and dietary modifications for managing PCOS symptoms but reports no new clinical results; the authors emphasize the importance of early diagnosis and management to prevent associated health issues.
91 citations
,
April 2017 in “Diabetes & Metabolic Syndrome: Clinical Research and Reviews” This review discusses the role of dietary habits and lifestyle modifications in managing polycystic ovary syndrome and reports no clinical results; the authors emphasize the need for tailored diet therapy in affected women.
441 citations
,
May 2008 in “British Journal of Pharmacology” This article reviews the potential clinical use of anabolic steroids in treating muscle loss from chronic diseases and aging and highlights both the benefits and risks of these substances in sports.
March 2026 in “Journal of Cancer Survivorship” This review highlights the potential for physical exercise to reduce treatment toxicity and modification rates in patients with metastatic colorectal cancer receiving systemic treatments, suggesting benefits for survival outcomes; it recommends further trials to confirm these findings.
114 citations
,
January 2014 in “World Journal of Gastroenterology” This study highlights the potential increased frequency of advanced liver disease in obese PCOS patients with NAFLD and underscores the importance of lifestyle modifications as initial treatment.
89 citations
,
November 2014 in “Medical Clinics of North America” This article reviews management strategies for PCOS and reports no new clinical results; the authors highlight oral contraceptives, lifestyle modifications, and metformin as key interventions.
9 citations
,
September 2016 in “Medical Clinics of North America” This review discusses strategies for weight loss in obesity through dietary energy deficits and nutrient profile modifications and highlights the need for personalized dietary approaches; it reports no new data.
4 citations
,
June 2021 in “Basic and Clinical Neuroscience Journal” In this study, transplantation of rat hair follicle stem cells significantly improved sciatic nerve regeneration and muscle function in nerve-injured rats.
3 citations
,
October 2022 in “Han'gug dongmul jawon gwahag hoeji/Han-guk dongmul jawon gwahak hoeji/Journal of animal science and technology” This study found that L-glutamine supplementation in Hanwoo steers under heat stress did not affect growth performance or muscle and adipose tissue gene expression but was associated with increased immune cells and reduced HSP90 expression.
September 2022 in “International Journal of Health Sciences and Research” In this study, both resistance training and aerobic exercise with lifestyle modification were similarly effective for managing PCOS symptoms, but resistance training showed more significant benefits for BMI and menstrual regularity.
425 citations
,
January 2021 in “SN Applied Sciences” This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.
85 citations
,
December 2017 in “Developmental Biology” This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.
1 citations
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May 2023 in “Farmacja Polska” This study summarizes current knowledge on the role of creatine in the human body, its applications in supplementation, and its impact on muscle mass, especially noting that animal-based foods are primary dietary sources and that women may experience health benefits from supplementation.
March 2025 in “Pakistan Journal of Scientific & Industrial Research Series A Physical Sciences” This abstract discusses the challenges of diagnosing and managing PCOS, highlighting that individualized management, lifestyle modifications, and medical treatments such as contraceptives and metformin are recommended to address hormonal imbalances and co-morbidities.
January 2024 in “Wiadomości Lekarskie” This study outlines new strategies for overcoming "cold" tumors, which are typically unresponsive to cancer immunotherapy, with approaches like dendritic cell-based treatments and local immune microenvironment modification, bolstered by both preclinical and clinical trial data.
December 2021 in “THE THERAPIST (Journal of Therapies & Rehabilitation Sciences)” This review highlights the increased need for awareness about Polycystic Ovarian Syndrome (PCOS) and suggests that more research is necessary to understand its management through lifestyle modifications.
2 citations
,
December 2025 in “Nature Communications” This study found that the repressive histone mark H2AK119ub links inhibitory FGF signals with the quiescent state in hair follicle stem cells, revealing a signaling-epigenetic axis crucial for maintaining stem cell quiescence and tissue homeostasis.
67 citations
,
September 2017 in “Cell Reports” Caloric restriction improves skin and fur structure but can cause muscle loss and movement issues.
19 citations
,
August 2018 in “Clinics in plastic surgery” This review discusses surgical techniques for facial and neck modifications in gender dysphoria and reports no new clinical outcomes.
The document recommends a multidisciplinary approach and experience sharing to advance facial feminization surgery as a medical field.
28 citations
,
December 2013 in “British Journal of Oral & Maxillofacial Surgery” This article reviews age-related changes in facial structure at a cellular level and summarizes potential solutions for rejuvenation surgery, but reports no new clinical results.
18 citations
,
January 2017 in “Dermatologic Surgery” This review examines intrinsic and extrinsic aging impacts and presents evidence-based lifestyle recommendations to complement cosmetic procedures for enhanced antiaging outcomes, but it reports no new clinical results.
418 citations
,
September 2012 in “Nature” This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.
112 citations
,
January 2014 in “Molecular and cellular therapies” This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.
104 citations
,
November 1978 in “JAMA” This article reviews the challenges of fasting and dietary regimens in producing sustained weight loss and reports no new research findings or results.
96 citations
,
September 2021 in “International Journal of Molecular Sciences” This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.
33 citations
,
April 2011 in “Journal of Veterinary Internal Medicine” This study found that inhaled fluticasone for 11 months did not adversely affect the immune function or response to vaccination in horses with heaves.
4 citations
,
May 2025 in “Stem Cell Research & Therapy” This review explores the potential of extracellular vesicle therapy as a novel strategy to delay intervertebral disc degeneration and enhance tissue repair, by modulating key pathogenic mechanisms, with a focus on the molecular components and bioengineering modifications of extracellular vesicles.
1 citations
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June 2025 in “Pharmacia” This study highlights the growing use of botulinum toxin in both medical and cosmetic fields, showing its benefits and risks. Proper administration is crucial to avoid severe side effects like muscle weakness and respiratory issues, emphasizing the need for enhanced safety measures and regulations.