research Androgen Receptor Modulators: A Review of Recent Patents and Reports (2012-2018)
New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
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research The Use of Neurotoxins in the Male Face
Men need higher doses of botox than women and a different approach for facial aesthetics due to their unique facial features and muscle mass.
research Patched-Associated Tumors: Modifier Genes and Pathogenesis
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Tailored Chromatin Modulation to Promote Tissue Regeneration
Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
research Lecithin Organogels as a Potential Phospholipid-Structured System for Topical Drug Delivery: A Review
Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.
research The Frequency of Visceral and Phenotypic Markers in Patients with the Combination of Undifferentiated Connective Tissue Disease and Gastroesophageal Reflux Disease
Patients with both connective tissue disease and acid reflux are more likely to have certain symptoms and physical signs.
research Complications of Cushing's Syndrome: State of the Art
Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.
research The Selective Androgen Receptor Modulator GTx-024 (Enobosarm) Improves Lean Body Mass and Physical Function in Healthy Elderly Men and Postmenopausal Women: Results of a Double-Blind, Placebo-Controlled Phase II Trial
Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
research Androgen Therapy in Women: An Endocrine Society Clinical Practice Guideline
The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
research Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration
Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
research Global Adiposity Rather Than Abnormal Regional Fat Distribution Characterizes Women with Polycystic Ovary Syndrome
Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.
research Lifestyle Intervention and Anti-Obesity Therapies in Polycystic Ovary Syndrome: Impact on Metabolism and Fertility
Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.
research Lamins in Development, Tissue Maintenance, and Stress
Lamins are vital for cell survival, organ development, and preventing premature aging.
research Bioengineered Plants as a Source of Omega-3 Fatty Acids
Genetically modified plants could be an important source of omega-3 fats to meet global needs.
research Physiopathology and Current Treatments of Androgenetic Alopecia: Going Beyond Androgens and Anti-Androgens
Hair loss treatments work better with lifestyle changes.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair
The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
research Stiffness-Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory
The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.
research Defining the Identity of Mouse Embryonic Dermal Fibroblasts
Researchers identified specific genes that are important for mouse skin cell development and healing.
research Epigenetic Regulation in Adult Stem Cells and Cancers
Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
research Progress and Prospects: Gene Therapy for Performance and Appearance Enhancement
Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.
research The Corpus Cavernosum After Treatment With Dutasteride or Finasteride: A Histomorphometric Study in a Benign Prostatic Hyperplasia Rodent Model
Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.
research Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue
The document concludes that the technique allows for the detection of LDH activity in various tissues, showing where cells are actively metabolizing glucose.
research Controversy: Is There a Role for Adjuvants in the Management of Male Pattern Hair Loss?
Adjuvants, diet changes, and laser therapy may improve male pattern hair loss.
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Can Resistance Training Improve the Symptoms of Polycystic Ovary Syndrome?
Resistance training might help with PCOS symptoms, but more research is needed.
research Extraction and Detection of mRNA from Horsehair
RNA can be extracted from horsehair roots for analysis.
research Environment of the Anagen Follicle
The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
research New Insights Into Inflammatory Memory of Epidermal Stem Cells
Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.