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The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Skin fat cells help with skin balance, hair growth, and healing wounds.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Skin fat helps with body temperature control and has other active roles in health.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

New treatments for male hypogonadism are effective and should be personalized.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Advanced human skin models improve drug development and could replace animal testing.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Keratinocytes control how melanocytes work.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Hair follicle stem cells can turn into various cell types and help repair nerves.

Pannexin 3 is important for bone formation and the development of bone cells.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

DNA methylation changes are linked to hair growth cycles in goats.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.