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The SGAP flap effectively treats large sacral pressure sores with good results and minimal complications.

Finasteride can cause multiple side effects like tremors, dry skin, and rapid aging.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Stem cells in hair follicles can become various cell types, including neurons.

Peptides, proteins, and growth factors in skincare show promise for improving skin health.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Hydralazine and minoxidil are blood pressure medications that relax blood vessels, with potential side effects like rapid heartbeat and fluid retention, and are used for severe or pregnancy-related hypertension.

Hair follicle stem cells can turn into various cell types and help repair nerves.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

The patient had paraneoplastic pemphigus without mucosal involvement.

Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.

The document concludes that understanding the anatomical changes of the ageing face is important for effective rejuvenation treatments.