1 citations,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
52 citations,
October 1999 in “Developmental Dynamics” Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
4 citations,
June 2021 in “Journal of Microbiology and Biotechnology” Ginsenoside Rg4 from ginseng may help hair growth by activating certain cell signals.
50 citations,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
November 2023 in “Periodontology 2000” Injectable platelet-rich fibrin has improved healing and regeneration in various medical fields and can be more effective than previous treatments.
January 2019 in “Springer eBooks” Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
February 2024 in “Frontiers in physiology” Modifying certain signals in the body can help wounds heal without scars and regrow hair.
3 citations,
June 2021 in “Frontiers in genetics” The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
7 citations,
September 2017 in “Biomedical and Pharmacology Journal” Growth factors greatly affect hair loss, with different levels seen in men, women, younger patients, and at the start of the condition.
June 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The skin basement membrane is specialized for different tissue interactions, important for hair growth and attachment.
32 citations,
March 2021 in “Journal of endocrinological investigation” Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
25 citations,
July 2017 in “Journal of Stomatology, Oral and Maxillofacial Surgery” PRP injections help regrow hair, reduce hair loss, and increase hair thickness, but effects decrease without ongoing treatment.
31 citations,
January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
131 citations,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
243 citations,
October 2003 in “Developmental biology” Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.
10 citations,
May 2016 in “Journal of Dermatological Science” PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
24 citations,
October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
82 citations,
May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
63 citations,
May 2009 in “Dermato-endocrinology” Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.
August 2020 in “Research Square (Research Square)” Neural progenitor cell-derived nanovesicles help hair growth by activating a key signaling pathway.
51 citations,
August 2012 in “Differentiation” Mouse genital development depends on male or female hormones for specific features.
112 citations,
January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
43 citations,
December 2013 in “Seminars in Cell & Developmental Biology” Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
119 citations,
July 2016 in “Annals of the New York Academy of Sciences” Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
155 citations,
August 2003 in “Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution” Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
236 citations,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
41 citations,
August 2015 in “The FASEB Journal” Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.
October 2023 in “Biomaterials” Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
7 citations,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.