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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Use minoxidil for hair loss treatment; assess results after 6 months.

Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

The document concludes that molluscum contagiosum is a common, benign skin infection in children, often healing without scarring.

Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

A patient with alopecia areata regrew hair after taking tofacitinib and showed changes in certain blood and skin markers.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Subcutaneous contraceptives can cause side effects like menstrual changes, headaches, weight gain, and pain at the implant site.

Hair loss in cancer patients can be related to the cancer itself, treatment, or other conditions, and understanding it is important for diagnosis and patient care.

Both tissue expansion and serial excision are effective for scar revision in the head and neck area.

Most new moms had their hair grow back within 4-6 months after childbirth, and hair loss is likely due to hormonal changes.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.