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Prednisone reduces organ mast cell infiltration but does not alter the abnormal appearance of mast cells in systemic mastocytosis.

A patient with Cronkhite-Canada syndrome improved with nutritional support and steroids, but early diagnosis is key due to high mortality.

Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.

New cancer treatments are less harmful to hair but can still cause hair loss, color, shape, and growth changes.

There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

The document concludes that there have been significant improvements in diagnosing and treating skin diseases, including melanoma, with new techniques and therapies.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Targeted cancer therapies often cause serious skin problems that need careful management.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.