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The review shows that skin symptoms like chronic fungal infections, hair loss, and skin depigmentation are key for early detection and management of APECED.

Early recognition and treatment of tinea capitis are crucial to prevent severe scalp issues and prolonged therapy.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.

Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.

Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Ozone therapy might improve cancer treatment and reduce its side effects.

Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.

The combined treatment with engineered bacteria and yellow LED light improved wound healing in mice.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.

Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.

Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.

A new non-invasive method can analyze skin mRNA to understand skin diseases better.

Hair analysis can show nutritional status and environmental exposure, with phosphorus being very stable in hair and differences found based on gender and conditions like depression and autism.

Topical botanical lotion increases hair density and improves quality of life in women with hair loss.

Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.

CTHRC1 helps hair grow back, and plantar dermis mixture boosts it.

The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.

Women with PCOS tend to be less optimistic than those without it.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

New oral treatment, finasteride, effectively and safely treats common hair loss.