July 2026 in “Frontiers in Medicine” This review explores the evidence for platelet-rich plasma, exosomes, and other regenerative therapies as adjuncts in hair transplantation, finding that PRP has the most support, but highlights the need for standardization and transplantation-specific studies.
28 citations
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September 2020 in “International Journal of Molecular Sciences” This study concluded that leucocyte-rich PRP has a continuous stimulatory effect on human fibroblast cells, enhancing their proliferation, migration, and impacting gene expression of the extracellular matrix and adhesion molecules.
6 citations
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May 2024 in “Frontiers in Pharmacology” This review discusses the potential of natural products to induce ferroptosis as a promising therapeutic strategy for non-small cell lung cancer and reports no clinical results; the authors highlight the need for further comprehensive studies.
27 citations
,
September 1992 in “The Lancet” ICL is a condition with low CD4+ T cells like AIDS but not caused by HIV, and normal CD4+ T cell counts may vary between men and women.
2 citations
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July 2025 in “Frontiers in Veterinary Science” This review highlights that microRNAs (miRNAs) play crucial roles in hair follicle development and cycling in cashmere goats, detailing recent advances in understanding their regulatory functions and potential applications in improving cashmere fiber quality and diagnosing hair disorders.
1 citations
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February 2025 in “Frontiers in Nutrition” This study found that a postbiotic derived from hawthorn and probiotics can alleviate loperamide-induced constipation in aged mice by regulating several physiological processes, including intestinal water and sodium metabolism, maintaining gut flora and barrier, reducing inflammation, and enhancing short-chain fatty acid metabolism.
June 2024 in “Computational and Structural Biotechnology Journal” This review discusses the integration of omics analyses in androgenetic alopecia research, reporting no new clinical results but suggesting that collaborative multi-omics studies may enhance understanding of AGA's pathomechanisms.
February 2023 in “Archives of Dermatological Research” This study found that despite challenges, a combination of oral antibiotics, anti-androgens, oral retinoids, biologics, and surgery were important in managing hidradenitis suppurativa in patients with intellectual and developmental disabilities.
2 citations
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February 2022 in “Frontiers in Endocrinology” This study found that antiandrogenic pretreatment with combined oral contraceptives did not improve ovulation and pregnancy outcomes compared to direct letrozole induction in women with PCOS.
9 citations
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June 2025 in “Journal of Clinical Medicine” The authors concluded that while PRP is a promising and well-tolerated treatment for early to moderate knee osteoarthritis, standardizing preparation protocols, patient selection, and outcome reporting is crucial to enhance comparability and inform clinical practice.
February 2026 in “Journal of the Grodno State Medical University” This review covers the application of platelet-rich plasma therapy across multiple medical fields, noting its widespread use and safety but also highlighting the need for further research.
July 2025 in “Journal of Clinical Medicine” In this review, platelet concentrates were found to show comparable efficacy to steroids and immunosuppressive drugs in treating oral lichen planus, with some studies reporting more benefits and others noting more severe adverse reactions with platelet treatments.
September 2025 in “Journal of Neonatal Surgery” This study found that platelet-rich plasma therapy significantly improved hair density and reduced hair loss in patients with androgenetic alopecia over six months, but lacks a comparative placebo or alternative treatment group.
22 citations
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October 2024 in “Advanced Healthcare Materials” This study demonstrated that gelatine-based hydrogel foams loaded with platelet extracellular vesicles (pEVs) promoted full wound closure in a chronic wound rat model within 14 days, suggesting potential for personalized treatment of chronic diabetic wounds.
3 citations
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January 2024 in “Cell Transplantation” This study reviews various factors affecting mesenchymal stem cell transplantation efficacy, including platelet concentrate composition, donor characteristics, and environmental influences, and examines strategies for optimizing outcomes through preconditioning and combined therapies in regenerative medicine.
2 citations
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January 2025 in “Journal of Experimental Orthopaedics” Platelet-rich plasma does not improve recovery after Achilles tendon surgery.
2 citations
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April 2022 in “Indian Journal of Dermatology, Venereology and Leprology” This pilot study suggests that platelet-rich plasma may be a promising treatment for chronic telogen effluvium with good safety, and cost-effective preparation methods may be reliable alternatives to more expensive ones.
1 citations
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April 2025 in “Journal of Cosmetic Dermatology” This study found that using Alastin Restorative Skin Complex Serum 2.0 with TriHex Technology for 12 weeks significantly improved facial skin hydration, elasticity, and overall quality in individuals with moderate to severe skin aging, with histological evidence showing new collagen and elastin fibers.
1 citations
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September 2023 in “Journal of cosmetic dermatology” In this retrospective observational study, the researchers evaluated autologous FUE hair transplantation for nine patients with secondary scarring alopecia from infections, reporting 88.9% satisfaction 12 months post-surgery and minimal complications, suggesting it is an effective and minimally invasive treatment option.
1 citations
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March 2019 in “International Journal of Molecular Medicine” This study demonstrated that hair follicle cells can be induced to differentiate into cardiomyocyte-like cells in vitro, exhibiting characteristics and spontaneous beating typical of cardiac muscle, without genetic modification.
November 2025 in “Aesthetic Surgery Journal Open Forum” This meta-analysis reported that platelet-rich plasma significantly improved patient satisfaction and objective efficacy in treating skin aging, while not significantly increasing adverse effects.
October 2025 in “Skin Health and Disease” This review found preliminary evidence suggesting that photothermal conditioning enhances the bioactivity of platelet-rich plasma, potentially improving hair regeneration outcomes, but highlights the need for standardized protocols and further studies to confirm its efficacy and safety.
July 2024 in “Periodontology 2000” This review summarizes the use of autologous platelet concentrates in aesthetic medicine, finding promising results for facial treatments, but highlights the need for more rigorous research due to current study limitations.
53 citations
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August 2014 in “Cochrane library” This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.
25 citations
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August 2021 in “Irish Journal of Medical Science (1971 -)” This study found that COVID-19 infection is a frequent cause of acute telogen effluvium, leading to excessive hair loss within 2–3 months after infection.
8 citations
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July 2025 in “Gels” This review discusses how functionalized hydrogels can modulate the microbiome to aid tissue regeneration and infection control, highlighting their potential to deliver therapeutic agents effectively and support beneficial immune responses.
1 citations
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July 2025 in “Chemosensors” This study developed a closed-loop system for emergency wound care that monitors infection in real-time using biomarkers and delivers amikacin-loaded liposomes for treatment, integrating a conductive hydrogel for environmental protection and antibacterial benefits.
1 citations
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May 2017 in “InTech eBooks” This review discusses various scalp infections, infestations, and neoplasms but reports no new clinical findings; the authors emphasize the diversity of diseases from different origins.
December 2024 in “Anti-Aging Eastern Europe” This study highlights the potential of Platelet-Rich Plasma (PRP) as an effective treatment for improving skin texture, tone, and elasticity, and treating hair loss, warranting further research to optimize its use in aesthetic dermatology.
3 citations
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June 2025 in “Biomedicines” This review discusses the potential link between gut microbiota alterations and the onset and progression of alopecia areata, identifying it as a possible pathogenetic factor and therapeutic target, but reports no new clinical results.