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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Polycystic ovary syndrome affects about 6-10% of women, with varying symptoms and the need for standardized global definitions.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Corporate social responsibility can improve consumer ratings of product performance, especially when the company is seen as benevolent and consumers aren't experts on the product.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Targeting colon cancer stem cells might lead to better treatment results.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.