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Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

A woman had severe reactions to methotrexate, including skin issues and organ problems, but improved after 38 days in the hospital.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

A dog with unusual skin lesions near its tail was successfully treated for a rare form of lupus.

A 12-year-old boy with a rare genetic condition has progressive hair loss with no effective treatment.

The document suggests a possible link between mast cells and scarring alopecia, recommending more research for potential treatments.

Skin issues like hair loss, rash, and sensitivity to sunlight are key signs of lupus activity.

Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.

Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Patients with chronic graft-versus-host disease often have skin problems like vitiligo and alopecia areata.

Hair loss in autoimmune blistering skin diseases varies and may regrow with disease control.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

COX-2 and Bcl-2 proteins are involved in Lichen Planus.

Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

Linear Discoid Lupus Erythematosus of the scalp can cause hair loss and should be considered in similar cases.

A rare skin condition affected only the facial hair of a 46-year-old man.

Cancer treatments can cause hair loss, but it is often reversible and can be managed with scalp cooling and support.

Oral minipulse therapy effectively treated bullous lichen planus in a 35-year-old woman.

Most patients with Lichen planopilaris improved with acitretin, but treatments often didn't work well; preventing infection in skin surgery is important, and bupivacaine might be a better anesthetic.

Sarcoidosis can cause various skin issues, making diagnosis difficult.

The research found that androgens help control blood flow in the rat prostate through a specific binding site.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Baby's toe injury linked to mom's hair loss; check baby's toes and be careful with fruit gel snacks.