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The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

AIRE deficiency causes hair loss similar to alopecia areata in mice.

The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

The interdigital gland in crossbred sheep is similar to skin and has specialized structures for secretion.

Epithelial proliferation and hyperkeratosis are linked to gastric ulcers in pigs.

The document describes previously unreported unique skin changes in a rare genetic disorder called Hereditary mucoepithelial dysplasia.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Red clover extract improved hair, skin, mood, sleep, and tiredness in postmenopausal women.

Lichen planopilaris in men often involves scalp redness and itching, with some also having hair loss, mucosal lichen planus, or thyroid disease, and treatment improved symptoms in nearly half of the cases.

A rare type of skin cancer with mucosal involvement was partially treated but eventually relapsed.

Cronkhite-Canada syndrome can be diagnosed without gastrointestinal polyps if there is severe mucosal atrophy and edema.

Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Oral ulcers are common in SLE patients and often link to other symptoms.

Myoepithelial cells can repair airways after severe injury.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.

Early regulatory T cells are crucial for normal skin pigmentation.

Benign follicular mucinosis involves immune cells attacking hair follicles.

MAIT cells may help fight COVID-19 but also contribute to severe inflammation.

Regular endoscopic checks are crucial for Cronkhite-Canada syndrome patients to catch potential cancers early.