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Different harmful mutations in the CDH3 gene cause HJMD, but symptoms vary among individuals.

The document discusses various diseases of the outer ear, categorized by symptoms like redness, crusts, bumps, pus-filled lesions, lumps, ulcers, and hair loss.

Lichen planopilaris in men often involves scalp redness and itching, with some also having hair loss, mucosal lichen planus, or thyroid disease, and treatment improved symptoms in nearly half of the cases.

Anti-Desmocollin 3 antibodies can cause pemphigus-like symptoms in mice.

Some acne medications have side effects; doctors should educate patients and may not need to do frequent lab tests for all.

Newer retinoid drugs are effective for skin conditions but have significant side effects.

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

HIV can cause skin disorders, which are often the first sign of infection, especially in people with darker skin.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Systemic lupus erythematosus is a chronic disease causing inflammation and various symptoms, mainly in young women, treated with anti-inflammatory and immunosuppressive drugs.

A young tapir with a rare skin condition improved after treatment with wound cleaning, cream, and oral medication.

Early recognition and treatment of SLE can improve outcomes in patients with complex symptoms.

Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.

The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.

Kawasaki's disease can occur in adults and should be considered with specific symptoms and high ferritin levels.

A woman with acne and baldness was found to have a rare ovarian condition but successfully had a child through fertility treatment.

Vitamin B12 deficiency can cause reversible hair color loss in children.

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

Traditional Chinese medicines with heavy metals can cause severe poisoning.

Removing the thymoma improved the man's autoimmune conditions.

A patient with zinc depletion improved after zinc supplementation during parenteral nutrition.

A newborn with congenital syphilis had unusual hair loss possibly caused by the infection.

A Doberman Pinscher had a rare form of autoimmune disease causing hair loss and other severe symptoms.