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      Interferon Alfa-2a in the Treatment of Cutaneous T Cell Lymphoma

      research Interferon alfa-2a in the treatment of cutaneous T cell lymphoma

      209 citations , March 1989 in “Journal of The American Academy of Dermatology”
      This study found that recombinant human leukocyte interferon alfa-2a achieved a 64% overall antitumor response rate in patients with early and advanced cutaneous T cell lymphoma and was generally well-tolerated.
      Treatment of Alopecia Areata With Tofacitinib

      research Treatment of Alopecia Areata With Tofacitinib

      78 citations , March 2017 in “JAMA Dermatology”
      Tofacitinib helped regrow hair in people with severe alopecia, but side effects occurred and benefits stopped after treatment ended.
      Methotrexate in Dermatology

      research Methotrexate in dermatology

      77 citations , July 2007 in “Dermatologic Therapy”
      This review discusses methotrexate's use in dermatology and its mechanisms, pharmacokinetics, dosing, side effects, interactions, and emphasizes the need for further research into optimizing therapy and predicting adverse events.
      Effects of Dermatological Medications on Male Fertility

      research Dermatological medication effects on male fertility

      55 citations , July 2013 in “Dermatologic therapy”
      This review explores the impact of various medications on male fertility, highlighting reversible negative effects from methotrexate, finasteride, and ketoconazole, while reporting no adverse fertility effects for oral retinoids and certain immunosuppressants.
      Dupilumab: A Review of Present Indications and Off-Label Uses

      research Dupilumab: A Review of Present Indications and Off-Label Uses

      50 citations , March 2021 in “Journal of investigational allergology & clinical immunology”
      This review examines existing research and clinical trials on the use of dupilumab for various skin, respiratory, and gastrointestinal disorders, but it reports no new clinical findings.
      Microneedle-Based Approaches for Skin Disease Treatment

      research Microneedle-Based Approaches for Skin Disease Treatment

      48 citations , February 2025 in “Nano-Micro Letters”
      This review summarizes the application of microneedles in treating various skin diseases and highlights challenges like low drug loading, noting no new clinical results are reported.
      Recent Studies on the Delivery of Hydrophilic Drugs in Nanoparticulate Systems

      research Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems

      47 citations , September 2015 in “Journal of Drug Delivery Science and Technology”
      This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.
      Emerging Treatments in Alopecia

      research Emerging treatments in alopecia

      47 citations , October 2014 in “Expert Opinion on Emerging Drugs”
      This review discusses emerging treatments and mechanisms for alopecia, highlighting potential therapies like janus kinase inhibitors and advances in stem-cell technology, but reports no new experimental results.
      Baricitinib: From Rheumatoid Arthritis to COVID-19

      research Baricitinib: From Rheumatoid Arthritis to COVID‐19

      42 citations , April 2021 in “Journal of clinical pharmacology”
      This review discusses baricitinib's applications for various inflammatory disorders and highlights its promising efficacy alongside potential adverse effects, advocating for further research before it becomes a standard treatment.
      Medical Therapy for Frontal Fibrosing Alopecia: A Review and Clinical Approach

      research Medical therapy for frontal fibrosing alopecia: A review and clinical approach

      37 citations , April 2019 in “Journal of The American Academy of Dermatology”
      This review assessed the effectiveness of various treatments for frontal fibrosing alopecia and found that intralesional steroids and 5α-reductase inhibitors showed the most positive outcomes in slowing or halting hair loss, though the lack of placebo-controlled studies and consistent outcome measures limits definitive conclusions.
      Systematic Review and Meta-Analysis of the Efficacy and Safety of Leflunomide and Methotrexate in the Treatment of Rheumatoid Arthritis

      research Systematic review and meta-analysis of the efficacy and safety of leflunomide and methotrexate in the treatment of rheumatoid arthritis

      37 citations , September 2017 in “Reumatología Clínica”
      In this systematic review and meta-analysis, methotrexate and leflunomide were compared for treating rheumatoid arthritis, showing similar efficacy overall. Methotrexate reduced swollen joints more effectively, while leflunomide was associated with fewer gastrointestinal side effects but more frequent liver enzyme increases.
      Autoimmune Disease and Hair Loss

      research Autoimmune Disease and Hair Loss

      35 citations , October 2012 in “Dermatologic Clinics”
      This article reviews the impact of different forms of alopecia on patients with systemic autoimmune diseases and reports no new clinical findings; it emphasizes the need for attentive management of alopecia-related symptoms.
      Patients With Specific Skin Disorders Affected by COVID-19: What Do Experiences Say About Management Strategies? A Systematic Review

      research Patients with specific skin disorders who are affected by COVID ‐19: What do experiences say about management strategies? A systematic review

      31 citations , June 2020 in “Dermatologic Therapy”
      This systematic review reports that for patients with underlying dermatologic disorders who contracted COVID-19, most experienced mild to moderate exacerbation of their skin conditions and were managed similarly to the general population, suggesting treatment discontinuation during acute infection may prevent severe recurrence.
      Alopecia Areata: A Long-Term Follow-Up Study of 104 Patients

      research Alopecia areata: a long‐term follow‐up study of 104 patients

      29 citations , March 2019 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”
      This study found that the severity, duration, and relapse rate of alopecia areata decreased with older age at onset, while relapses mostly occurred early and declined over time.
      Comprehensive Overview of Hidradenitis Suppurativa

      research Hidradenitis Suppurativa

      27 citations , December 2015 in “Mayo Clinic Proceedings”
      This review presents an evidence-based algorithm for managing hidradenitis suppurativa in primary care, highlighting the need for more research on treatment effectiveness and the disease's pathogenesis.
      Intralesional Therapy for the Treatment of Keratoacanthoma

      research Intralesional therapy for the treatment of keratoacanthoma

      25 citations , March 2019 in “Dermatologic therapy”
      This study reviewed the current state of intralesional therapy for keratoacanthoma, finding that while methotrexate, 5-fluorouracil, and interferon alpha are common agents, guidelines are still needed, and histopathological confirmation is advised to prevent misdiagnosis with squamous cell carcinoma.
      Interventions for Morphea

      research Interventions for morphea

      24 citations , July 2019 in “Cochrane library”
      This review found that oral methotrexate plus oral prednisone may improve disease activity or damage in juvenile active morphea compared to placebo plus prednisone, but adverse events may slightly increase.
      Cicatricial Alopecia: Overview and Treatment Recommendations

      research Cicatricial alopecia

      23 citations , April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft”
      This review discusses the classification and diagnosis of primary cicatricial alopecias and reports no new clinical results; it highlights the need for effective treatments owing to limited evidence of current therapies' efficacy.