research Case Report: A Novel Splice-Site Mutation of MTX2 Gene Caused Mandibuloacral Dysplasia Progeroid Syndrome: The First Report from China and Literature Review
A new MTX2 gene mutation caused a severe genetic disorder in a young Chinese girl.
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30 / 214 results research Treatment of Rheumatoid Arthritis Patients: Comparative Efficacy of Four Treatment Regimens
MTX and GC combinations are the most effective for early rheumatoid arthritis.
research Methotrexate in the Treatment of Steroid-Dependent Asthma
Methotrexate reduced the need for steroids in asthma patients without worsening their condition.
research Efficacy and Tolerability of Methotrexate in Severe Childhood Alopecia Areata
Methotrexate sometimes helps regrow hair in children with severe alopecia areata and is generally safe.
research Efficacy and Safety of Methotrexate in Alopecia Areata
Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.
research Efficacy and Safety of Methotrexate Combined with Low- to Moderate-Dose Corticosteroids for Severe Alopecia Areata
Methotrexate with corticosteroids can effectively treat severe alopecia areata but often requires long-term maintenance.
research Patient’s Experience with Subcutaneous and Oral Methotrexate for the Treatment of Rheumatoid Arthritis
Methotrexate for rheumatoid arthritis often causes side effects like diarrhea, fatigue, and hair loss, especially at higher doses.
research High-Dose Pulsed Corticosteroid Therapy Combined with Methotrexate for Severe Alopecia Areata in Childhood
High-dose corticosteroids and methotrexate had a modest effect on severe childhood alopecia, but side effects and relapse were concerns.
research The Effect of Active Hexose Correlated Compound in Modulating Cytosine Arabinoside-Induced Hair Loss, and 6-Mercaptopurine- and Methotrexate-Induced Liver Injury in Rodents
AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.
research Is Methotrexate an Effective and Safe Treatment for Maintaining Hair Regrowth in People with Alopecia Totalis? A Critically Appraised Topic
Methotrexate's effectiveness for maintaining hair regrowth in alopecia totalis is unclear due to limited and biased data.
research Clinical Profile of Methotrexate-Resistant Juvenile Localized Scleroderma
Some children with localized scleroderma are rarely resistant to methotrexate, and no common profile for resistance was found.
research Methotrexate-Associated Lymphoproliferative Disorder: Sequential Development of Angioimmunoblastic T-Cell Lymphoma-Like Lymphoproliferation in the Lymph Nodes and Diffuse Large B-Cell Lymphoma in the Skin in the Same Patient
Stopping methotrexate might reverse lymphoma-like conditions in some patients.
research Hyperpigmentation, Severe Alopecia, and Six Days of Instability in a Case of Severe Methotrexate Hypersensitivity Reaction
A woman had severe reactions to methotrexate, including skin issues and organ problems, but improved after 38 days in the hospital.
research A Rare Case of Multiple Keratoacanthomas Treated with Oral Acitretin and Intralesional Methotrexate
A 25-year-old man with multiple skin tumors was successfully treated with acitretin and methotrexate.
research Review of Systemic Methotrexate Therapy in Pediatric Dermatoses
Methotrexate is effective and well-tolerated in children for certain skin conditions but requires careful monitoring.
research Comprehensive Overview of Rheumatology Studies: Ottawa, Ontario, Canada, February 13–16, 2013
The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
research Methotrexate Effectively Controls Ocular Inflammation in Japanese Patients With Non-Infectious Uveitis
Methotrexate effectively controls eye inflammation in Japanese patients with non-infectious uveitis but requires careful monitoring for side effects.
research Methotrexate Injection Site Reactions: Case Report and Literature Review
Methotrexate injection site reactions are rare but can be managed by changing injection sites and using topical treatments.
research Maculopapular Rash Upon Antibiotic Therapy in a Patient with Rheumatoid Arthritis
Methotrexate caused a rare skin rash in a rheumatoid arthritis patient, which resolved after stopping the drug.
research Comparative Analysis of Safety Data of Four Treatment Regimens in Early Rheumatoid Arthritis Patients
Methotrexate plus prednisolone had the fewest serious side effects.
research Intralesional Injection of Triamcinolone Acetonide, Methotrexate, and Vitamin D in Treatment of Alopecia Areata: A Narrative Review
Methotrexate and vitamin D3 are potentially more effective and safer than triamcinolone for treating localized alopecia areata.
research Adverse Effect Profile With Low-Dose Methotrexate Therapy in Patients Suffering With Rheumatic Diseases
Low-dose methotrexate is generally safe but can cause mild to severe side effects, and folic acid can reduce these risks.
research Methotrexate Treatment Patterns in Advanced Therapy-Naïve Patients with Rheumatoid Arthritis: Clinical Characteristics and Outcomes of Patients in the Corrona Registry
Most patients with rheumatoid arthritis continued methotrexate treatment over two years, but those who stopped and restarted experienced more side effects and less improvement.
research A 2018 Approach to Combating Methotrexate Toxicity: Folic Acid and Beyond
New strategies like vitamin A and dextromethorphan can help reduce methotrexate side effects and improve patient adherence.
research Safety of Four Treatment Regimens in Early Rheumatoid Arthritis
All four treatments for early rheumatoid arthritis had similar safety profiles.
research Methotrexate Treatment for Rheumatoid Arthritis in Poland: Retrospective Analysis of Patients in Routine Clinical Practice
Methotrexate is effective for treating rheumatoid arthritis but requires regular monitoring.
research Effects of High-Dose Daily Folate Versus Low-Dose Weekly Folate in Preventing Methotrexate Toxicity in Rheumatoid Arthritis Patients
Weekly 5 mg folate is enough to prevent methotrexate toxicity in rheumatoid arthritis patients.
research Methotrexate Dose Has Minimal Effects on Methotrexate-Related Toxicity in Patients with Early Rheumatoid Arthritis Treated in Combination with Adalimumab – Results of Concerto Trial
Methotrexate dose has little effect on its toxicity when used with adalimumab for early rheumatoid arthritis.
research Trends in the Presence or Absence of Transaminitis and/or Leukopenia in Pediatric Patients Treated with Methotrexate for Inflammatory Skin Disease
Most children with skin inflammation taking methotrexate had lab abnormalities, but liver issues often improved without changing the medication dose.
research Comparative Study Between Topical Methotrexate 1% Gel and Minoxidil 5% Gel in the Treatment of Localized Alopecia Areata
Minoxidil showed better improvement than methotrexate in treating localized alopecia areata.