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A new mutation in the FLCN gene linked to Birt-Hogg-Dube syndrome was found, suggesting people with certain lung collapse should be tested for this mutation and screened for kidney and colon cancer.

A low dose of rapamycin increases inner ear hair cell creation by boosting SOX2+ cell numbers.

Resistance exercise helps improve muscle protein balance disrupted by finasteride.

Acne patients have higher skin mTORC1 activity, which is reduced by isotretinoin treatment.

Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.

Skin problems from transplant drugs are common and need careful management in organ transplant patients.

Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.

Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.

Breast cancer patients taking CDK4/6 inhibitors are more likely to experience fatigue, hair loss, and mouth sores.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.

Acne patients have higher mTOR gene expression.

Raptor and Rictor have stable expression in hair cycles, with Raptor marking stem cells and Rictor involved in hair shaft formation.

Keeping human skin stem cells is easier with low temperatures and mTOR inhibition.

The April 2016 JEADV issue covered various dermatology topics, including psoriasis, psoriatic arthritis, mTOR inhibitors, autoimmune diseases, photodynamic therapy, viral DNA in skin diseases, chronic hand eczema, and female hair loss.

Copper-doxorubicin nanoparticles effectively treat tumors with less toxicity.

The document concludes that hair curvature can be explained by the growth patterns caused by the shape and separation of cells in the hair follicle and is affected by specific molecular pathways.

Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.

Minoxidil rejuvenates hair follicles and reduces aging signs in male pattern baldness.

Minoxidil helps hair regrowth and has anti-aging effects on hair follicles.

New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.

In 2023, there were major advancements in skin and venereal disease treatments.

Rapamycin treatment helps reduce brain inflammation and symptoms of mitochondrial disease by blocking specific pathways in mice.

Blocking mTORC1 activity could increase hair pigmentation and potentially reverse greying.

Most women with weird scalp feelings had neck spine problems, and some got better with gabapentin treatment.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.

Body-hair transplant successfully improved scarred areas and frontal hair density without visible chest scarring.

Keratosis pilaris is a common skin condition causing a bumpy texture, sometimes linked to other diseases, with various treatments available.