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Melatonin may protect inner ear cells from damage by reducing cell death and oxidative stress, potentially treating sudden hearing loss.

This study found that melatonin enhanced whisker growth in vitro and identified MT1 receptor presence in the granular layer of mouse epidermis and the outer root sheath, suggesting potential for hair growth treatment.

This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.

This review discusses the protective and stress-buffering roles of melatonin in skin functions and structures but does not present new clinical findings.

The researchers observed that normal murine hair follicles are direct targets for melatonin, with receptor expression varying throughout the hair cycle, suggesting melatonin's role in hair cycle control.

Scalp dermal papilla and fibrous sheath cells have different MMP expression than scalp dermal fibroblasts.

This chapter reviews existing knowledge about melatonin's MT₁ and MT₂ receptors in human tissues, discussing their established and potential functions, but reports no new clinical findings.

This study found that silencing SRD5A2 and applying melatonin significantly boosted proliferation and migration of human hair follicle stem cells without causing differentiation, while increasing MT1 expression and reducing 5-alpha-reductase levels.

This study found that normal murine hair follicles are direct targets for melatonin bioregulation, expressing receptors that are regulated in a hair cycle-dependent manner, influencing keratinocyte apoptosis.

This study highlights that topical melatonin formulations have the potential to increase hair density, prolong the hair growth phase, and reduce shedding in adults with alopecia, while generally being safe, though further large-scale randomized trials are needed to confirm its clinical efficacy.

This study found that Keratin 26 is expressed differently in hair follicle phases, particularly during catagen and telogen, influencing cashmere growth and interacting antagonistically with the BMP signaling pathway.

This study suggests that melatonin plays a role in hair follicle function by modulating growth and pigmentation, and it may act as a protective agent in active hair growth phases.

This study concluded that Finasteride can be effectively delivered in matrix tablets using different polymer ratios for sustained release.

This review discusses melatonin's potential in dermatology, highlighting its antioxidative, immunomodulatory, and DNA repair properties, but reports no new clinical results.

This study found that follicular stem cells in hair follicles are more sensitive to the antiproliferative effects of glucocorticoids compared to basal keratinocytes due to incomplete desensitization.

This case report describes the first known instance of hair loss linked to agomelatine, which resolved after the drug was discontinued.

Agomelatine might help stop hair loss caused by valproate.

This study reviews melatonin's diverse roles in dermatology, highlighting its potential to protect skin from UV damage and oxidative stress, enhance DNA repair, and influence hair follicle cycling, suggesting therapeutic applications in skin care and hair renewal.

This research found that melatonin plays a protective and modulatory role in skin biology, reducing UV damage and chemotherapy-induced hair follicle cell harm in human organ culture models.

This review discusses the safety of testosterone therapy for postmenopausal women and concludes that, aside from hirsutism and acne, it appears safe at physiological doses for several years, though more long-term studies are needed.

This study found that papain/bisulfite disintegrates human hair cuticles by dissolving the endocuticle, potentially accelerated by ethanol's removal of cell membrane material.

In this study, researchers explored the potential allergenicity and harmful effects of hair dyes, noting that adverse effects such as sensitization and potential carcinogenicity are not inevitable and can vary based on individual physiological differences.

This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.

This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.

This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.

This review discusses the roles of Eph receptors and ephrins in various diseases, highlighting their potential as therapeutic targets, but it presents no new research findings.

This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.

This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.

This study reports that miR-302 promotes pluripotency by inhibiting NR2F2 and indirectly regulating OCT4 in stem cells, enhancing reprogramming efficiency when added to traditional factors.

This study found that hair follicles in both mice and humans may serve as an important site for melatonin synthesis and signaling, potentially influencing hair cycle regulation by modulating keratinocyte apoptosis.