6 citations
,
April 2017 in “JAMA Dermatology” This study concluded that visits to emergency and urgent care centers for severe sunburn treatment are largely avoidable and contribute to significant healthcare costs.
5 citations
,
October 2018 in “Journal of Clinical Laboratory Analysis” This study found that improved testosterone measurement using LC-MS/MS in women with PCOS revealed a stronger correlation between hyperandrogenism and insulin resistance than previously detected.
5 citations
,
March 2015 in “Women's Health” This article reviews the process for diagnosing polycystic ovary syndrome and suggests how it can be applied in clinical practice but reports no new results.
4 citations
,
August 2022 in “The Scientific World Journal” This study found that bufotalinin, derived from Merremia peltata leaves, may enhance hair growth by acting as a potential androgen receptor antagonist in rabbits.
4 citations
,
May 2021 in “Molecules” This study suggests that analyzing hair samples with a liquid chromatography-mass spectrometric assay may offer a reliable method to measure average quarterly vitamin D levels, potentially complementing blood tests.
3 citations
,
November 2022 in “Separations” This study successfully established and validated a method using LC-MS/MS to measure multiple androgens in plasma, finding that individuals with acne had higher levels of certain androgens compared to those with obesity.
3 citations
,
May 2022 in “Clinical endocrinology” This study found that measuring certain steroids in hair can help diagnose and monitor congenital adrenal hyperplasia in Indonesian patients, offering a simple noninvasive method for developing countries.
3 citations
,
October 2021 in “Clinica Chimica Acta” This study found that higher levels of dihydrotestosterone in the parietal region of the scalp may correlate with the clinical presentation of androgenetic alopecia.
3 citations
,
July 2016 in “Tropical Journal of Pharmaceutical Research” This study found that the proposed LC-MS/MS method accurately quantified the drug content in split tablets of finasteride and terbinafine, revealing significant variability and suggesting that non-scored tablets should not be split.
2 citations
,
June 2025 in “Drug Testing and Analysis” This study found that after application of a testosterone cream containing 17α-methyltestosterone and testosterone propionate, these compounds could be detected in dried blood spots up to 97 hours post-application, potentially leading to sample contamination during fingertip puncture.
2 citations
,
September 2018 in “Journal of Separation Science” This study demonstrated that using finasteride impurity as a non-isotopically labeled internal standard in paper spray ionization–mass spectrometry can effectively and efficiently measure finasteride tablet dissolution, achieving results comparable to high-performance liquid chromatography.
2 citations
,
January 2012 in “Hair therapy & transplantation” This study observed that DDAIP-HCl enhanced the permeation of minoxidil through human cadaver skin, suggesting potential for improved treatment efficacy in male pattern hair loss.
1 citations
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September 2025 in “Molecules” This study comparatively evaluated different extraction techniques for Schinus terebinthifolius Raddi leaf extracts and found that conventional extraction with ethanol yielded the highest antioxidant activity and beneficial effects on skin cell viability, supporting its potential use in sustainable cosmeceutical formulations targeting skin aging.
1 citations
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November 2023 in “Endocrine Connections” This study developed a validated gas chromatography–tandem mass spectrometry assay to assess sex steroid hormones in cerebrospinal fluid, finding substantial levels of DHEA, androstenedione, and testosterone, with strong correlations to serum levels, providing insight into sex steroid dynamics in the human CNS.
1 citations
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May 2023 in “Frontiers in endocrinology” The researchers reported that the novel MBTPS2 variant p.Glu172Asp found in a male proband is likely pathogenic, consistent with osteogenesis imperfecta symptoms and molecular signatures, including disrupted fatty acid metabolism and collagen production.
1 citations
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October 2022 in “PubMed” This study identified 674 differentially expressed proteins in the skin tissues of male and female Chinese merino sheep, suggesting gender-specific molecular mechanisms that may affect wool traits.
1 citations
,
January 2017 in “UKnowledge (University of Kentucky)” This study found that while dutasteride significantly altered pregnane metabolism in mares during late gestation, it did not impact pregnancy outcomes, highlighting the complexity of pregnane metabolism and the necessity of LC-MS/MS for accurate measurement.
1 citations
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April 2015 in “Drug research” This study concluded that two different pharmaceutical formulations of finasteride were bioequivalent in terms of rate and extent of absorption based on pharmacokinetic evaluations in a randomized crossover study with 38 volunteers.
1 citations
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June 2014 in “Toxicologie analytique et clinique/Annales de toxicologie analytique” This study suggests that chest, arm, leg, and beard hair samples may be viable alternatives to scalp hair for monitoring long-term alcohol intake, although body hair is more typically collected from men.
1 citations
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December 2011 in “Arzneimittelforschung” This study developed a sensitive HPLC-MS/MS method for determining cyproterone acetate levels in human plasma and found no significant difference in its concentration between two oral formulations in bioequivalence testing.
June 2026 in “CUNY Academic Works (City University of New York)” This study developed and validated a method for measuring stress biomarkers in hair during pregnancy, finding that glucocorticoid levels increased over trimesters while endocannabinoid levels remained constant, suggesting hair analysis as a reliable tool for monitoring stress responses in pregnant women.
March 2026 in “Drug Testing and Analysis” This study observed that the degradation product PTeCA significantly increased in hair treated with oxidative cosmetics, suggesting it could be a reliable marker for detecting such treatments, with a proposed PTCA cut-off value using PTeCA as the gold standard.
November 2025 in “Molecules” This review examines recent advancements in green and emerging microextraction techniques, such as SPME and DLLME, for more sustainable hormone detection in biological samples, emphasizing environmentally friendly solvents and bioanalytical applications.
September 2025 in “International Journal of Cosmetic Science” This study observed that exposing human hair keratins to heat or UV treatments led to modifications in cysteine residues, disrupting crucial disulphide bonds and potentially reducing the structural integrity of hair similar to prolonged styling or sunlight exposure.
June 2025 in “JCEM Case Reports” In this case study, authors reported that a 43-year-old female patient initially showed persistently high testosterone levels due to immunoassay interference, later verified as normal using liquid chromatography-tandem mass spectrometry (LC-MS/MS), highlighting the need to consider assay artifacts in diagnosing hyperandrogenism without clinical signs.
January 2025 in “Revista Vitae” In this study, researchers found that 2 out of 9 analyzed cosmetic hair growth products contained the banned substance minoxidil, demonstrating the presence of this antihypertensive drug in some cosmetics despite regulations.
December 2024 in “Tropical Journal of Natural Product Research” This study evaluated the anti-alopecia effects of Petroselinum crispum leaf extracts in a rabbit model and through molecular docking analysis, finding that two ethyl acetate fractions promoted hair growth, with effects comparable to minoxidil, suggesting potential for alopecia treatment development.
This study found that androstenedione was more effective than testosterone in diagnosing hyperandrogenism in women with PCOS when measured by LC-MS/MS.
January 2024 in “Institutional Repositories DataBase (IRDB)” This study developed a method to measure local steroid hormone concentrations in hair, providing new insights into hormone dynamics associated with androgenetic alopecia.
December 2023 in “Kiểm nghiệm và An toàn thực phẩm/Kiểm nghiệm và An toàn thực phẩm (online)” This study developed a liquid chromatography with tandem mass spectrometry method to detect sex hormones in health supplements from Hanoi, Vietnam, finding three out of 16 samples contained sex hormones, including banned testosterone at low levels (~0.5 mg/kg).