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This study used whole-genome sequence data to identify numerous putative causal variants and genes affecting key wool traits and skin wrinkle in Merino sheep, highlighting their polygenic and pleiotropic nature.

This study suggests that longer GGN repeat polymorphisms in the androgen receptor gene are associated with polycystic ovary syndrome in women.

This study revealed gene expression patterns in yak hair follicles during different growth phases, enhancing the understanding of cell fate specialization and providing insights for yak villus development.

This study demonstrated that RNA interference targeting mutant keratin genes can effectively correct hair shaft structural defects in a mouse model by reducing mutant gene expression.

This study found that exposing adult esophageal epithelial cells to skin stroma can induce them to transition toward a hair follicle identity, with HIF1a playing a crucial role in this conversion process.

This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.

This study identified a crucial Gli2-Serpinh1 regulatory axis that regulates fibroblast state transitions during skin wound healing, shedding light on fibroblast heterogeneity and suggesting potential precision regenerative therapies.

In this study, researchers used single-cell RNA sequencing to map the hair follicle microenvironment in fine-wool sheep, identifying specific cell types and gene expressions that influence wool fiber diameter, with dermal papilla cells playing a significant role in hair follicle development.

This study mapped a detailed genetic profile of goat hair follicle apoptosis, identifying key genes and regulatory factors involved in the hair cycle, offering new insights into programmed cell death.

This study identified a high proportion of dual TCR Treg cells in both lymphoid and non-lymphoid tissues of mice, revealing their tissue specificity, TCR repertoire characteristics, and functional phenotypes.

This study reported that exosomes derived from human amniotic mesenchymal stem cells (hAMSC-exo) accelerated hair growth in androgenetic alopecia mice by enhancing signals between hair follicle cells and improving cellular environments, particularly protecting against dihydrotestosterone-induced damage via Wnt/β-catenin signaling.

In this study of Zhexi Angora rabbits, researchers found that the fine-wool group exhibited lower fiber diameters and a higher hair follicle density than the coarse-wool group, and they identified key candidate genes potentially regulating wool quality through RNA-seq and genome resequencing techniques.

This study found that palmoplantar pustulosis patients exhibited oral dysbiosis, particularly among those with pustulotic arthro-osteosis, as compared to healthy controls.

In this animal study, zinc deficiency in mice was linked to disrupted hair cycles and impaired hair regrowth, which were reversed by zinc supplementation.

This dissertation reported that the loss of Ovol2 impairs hair follicle regeneration and wound repair in mice, highlighting its role in regulating directional migration of epithelial cells.

This study identified numerous genes that change expression across the anagen, catagen, and telogen stages of cashmere goat hair follicle development, highlighting key signaling pathways involved.

This study found that overexpression of the FA2H gene in cashmere goats' hair follicle cells may enhance hair proliferation and regulate genes affecting cashmere fineness.

In this study, researchers examined chicken feather follicle tissues from differently colored chickens and found that the genes SLC45A2 and GPNMB are involved in promoting melanin deposition, which enriches understanding of the genetic mechanisms affecting feather color.

In this study, the researchers analyzed skin samples from Dun Mongolian horses to uncover molecular pathways linked to the "Bider" marking, identifying differential gene expression and several pigment-related signaling pathways that may play key roles in its formation.

This study found that Hetian sheep with higher wool density produce more and finer wool, with key genes potentially influencing their wool growth and density.

In this study, azelaic acid was found to enhance UVB protection in bulge cells and, when combined with minoxidil, may promote hair growth through increased Sonic hedgehog protein expression in hair follicles.

This study found that blocking the chemokine CXCL12 in a testosterone-induced mouse model of androgenetic alopecia restored hair regeneration and reduced fibrosis and immune alterations.

This study found that the topical Shen Bai hair growing decoction may improve androgenetic alopecia in mice by suppressing TNF-α and IL-6 levels, enhancing follicle density, and reducing apoptosis.

This study identified a stable combination of house-keeping genes, NCBP3 + SDHA + PTPRA, for normalizing gene expression in goat skin tissues using RNA sequencing.

This study found a significant association between reduced FGF13 levels and X-linked congenital generalized hypertrichosis, suggesting FGF13's potential role in hair follicle growth and the hair cycle.

This commentary highlights the potential of using transgenic and genome-edited mouse models to validate findings from livestock genomic and multi-omic analyses, aiding in the understanding of economically significant animal traits.

This study concludes that SPARC is likely a secondary response during the hair cycle's transitional phases, indicating tissue-remodeling processes similar to those in wound repair, rather than initiating these transitions.

In this study, researchers identified that keloid fibroblasts respond to neurotransmitters from catecholaminergic nerves by producing bone matrix proteins, mediated by β1-adrenergic receptor activation, leading to fibro-osseous reprogramming; blocking this signaling in a rodent model prevented the development of keloid-like pathology.

This study reports that PADI4, an enzyme involved in posttranslational protein modifications, regulates progenitor cell transitions in hair follicle development by repressing transcription and interacting with translational and ribosomal processes.

This study found that TLR3 activation in human keratinocytes enhances exosome biosynthesis and expression of hair follicle stem cell markers, suggesting a potential mechanism for tissue regeneration.