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COVID-19 may harm male fertility and damage the reproductive system.

Chicken feather gene mutation helps understand human hair disorders.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Long-term fluticasone treatment does not harm the immune system in horses with heaves.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

FoxN1 overexpression in young mice harms immune cell and skin development.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.