20 citations,
October 2008 in “Archives of dermatological research” Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.
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47 citations,
December 2019 in “Biomaterials” Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
55 citations,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
40 citations,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” S100A3 protein is crucial for hair shaft formation in mice.
25 citations,
June 2014 in “Journal of Endocrinology/Journal of endocrinology” Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
16 citations,
January 2019 in “Pharmaceutical biology” Lespedeza cuneata extract may help treat enlarged prostate.
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36 citations,
February 2017 in “BMC Complementary and Alternative Medicine” Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.
34 citations,
November 2011 in “Alcoholism: Clinical and Experimental Research” Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
38 citations,
June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
48 citations,
January 2011 in “Hormone Research in Paediatrics” The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.
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September 2016 in “Neuropharmacology” Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
August 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair growth supplements do not reduce the effectiveness of the breast cancer treatment tamoxifen.
5 citations,
June 2017 in “in Vivo” Vitamin C deficiency changes gene expression, affecting skin and hair health.
9 citations,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
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June 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” PAI-2 helps in the maturation and protection of hair and nail cells.
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May 2015 in “Neuropharmacology” Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
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15 citations,
January 1998 in “Journal of Clinical Periodontology” Finasteride helps treat hair loss by blocking enzyme activity.
August 2019 in “Journal of Invertebrate Pathology” Thymosin beta 4 protects cells from damage by blocking a harmful microRNA and boosting a protective gene.
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January 2017 in “Epilepsia” Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.
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January 2019 in “Elsevier eBooks” Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.
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April 2019 in “Biomolecules & Therapeutics” Udenafil may help hair grow by activating certain stem cells.
4 citations,
October 2014 in “Springer eBooks” Ethylene and auxin hormones interact in complex ways that are essential for plant growth and development.
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March 2021 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.
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January 2022 in “European Journal of Pharmacology” Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
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August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Modulating Cytochrome P450 activity could help develop new skin disease treatments.
3 citations,
December 2021 in “Frontiers in Pharmacology” Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.
May 2004 in “International Journal of Cosmetic Science” Melanogenesis inhibitors like kojic acid and niacinamide can reduce inflammation and pigment production in skin cells.
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May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” ELL is crucial for gene transcription related to skin cell growth.