Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study demonstrated that EdnrB signaling promotes melanocyte stem cell proliferation and differentiation, enhancing hair and epidermal melanocyte regeneration, especially under conditions of active Wnt signaling.

This article reviews major types of genetic hair shaft defects and associated syndromes, emphasizing understanding histologic features and diagnostic methods, but reports no new clinical findings.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

This article reviews the use of medical tattooing for cosmetic and therapeutic purposes across various fields, but reports no new clinical results.

Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.

This background review discusses alopecia areata, highlighting the role of CD8+NKG2D+ T cells in hair follicle pathogenesis, and notes that the exact mechanisms causing hair loss remain unclear.

This review discusses the roles of immune responses and cells in skin health and disease, emphasizing recent insights into their mechanisms and potential therapeutic applications, but presents no new experimental results.

This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.

This review discusses the emerging use of JAK inhibitors in alopecia areata treatment and reports no new clinical results; it highlights hair regrowth despite symptom recurrence after stopping therapy.

This study reports on eight previously unpublished cases of Bohring-Opitz syndrome with ASXL1 mutations, suggesting the importance of screening for Wilms tumors in these patients.

This study introduces the concept of teloptosis, which influences hair shedding during the telogen phase and affects hair density, highlighting that early or delayed teloptosis has noticeable effects.

This review found that JAK/STAT pathway inhibitors, such as tofacitinib and ruxolitinib, led to symptom improvement in all observed atopic dermatitis cases, but responses were mixed for vitiligo and alopecia areata, with a generally mild safety profile reported.

This study found that different epidermal stem cell populations contribute to the formation of various skin tumors and new hair follicles following β-catenin activation in the adult epidermis.

This chapter reviews keratins in skin epithelia, including their roles in cellular function and disease, and reports no new experimental results.

In this study, topical application of Thuja orientalis extract promoted hair growth by inducing the anagen phase and increasing hair follicle size and number in telogenic mice.

This study found that in scarring alopecia, stem cells are differentially localized, suggesting that both inner and outer root sheath stem cells, rather than just follicular bulge stem cells, are involved.

This speculative review discusses hair cycle-dependent fibroblast dynamics and possible impacts on human hair growth, synthesizing current literature without presenting new clinical findings.

Malnutrition severely harms growth and development in young baboons.

This study found that prolactin plays a direct role in regulating the timing of hair growth cycles in mice by affecting the skin, rather than through other endocrine factors.

In this study, expressing human K16 in the epidermis of K14 null mice prevented early skin blistering but led to age-related anomalies, indicating K16 and K14 have distinct roles despite their sequence similarity.

This review presents updated tables of mouse mutants with hair growth abnormalities to aid in understanding the molecular mechanisms of human hair disorders, but reports no new clinical results.

This article proposes three mechanisms by which dihydrotestosterone may contribute to baldness but reports no new research findings.

This study highlights that the mammalian target of rapamycin complex 2 (mTORC2)-Akt signaling axis is essential for hair follicle stem cells to return to their niche and regenerate effectively by regulating metabolic pathways.

In this study, tofacitinib treatment was associated with significant hair regrowth in two patients with alopecia universalis over eight months, with minimal adverse effects reported.

This article examines various types of childhood alopecia and highlights the importance of identifying chronic conditions or those linked to underlying medical issues, but reports no new results.

This review discusses the physiological changes in the female body during pregnancy, relating them to hormonal shifts, and comments on treatment considerations, but it presents no new research findings.

This review discusses various techniques for evaluating hair shedding and alopecia but reports no new clinical results. The authors emphasize the value of specific clinical and instrumental methods in assessing hair growth.

This study found that multiple treatment regimens for refractory hypertension were effective in controlling blood pressure in most patients, with diazoxide being the most effective but least tolerable option.

This study found that the antiandrogen drug enzalutamide reduced TMPRSS2 levels and significantly decreased SARS-CoV-2 entry and infection in lung cells, supporting further clinical trials for COVID-19 treatment.

This review examines existing research and clinical trials on the use of dupilumab for various skin, respiratory, and gastrointestinal disorders, but it reports no new clinical findings.