research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
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research Essential Thrombocythemia: The Dermatologic Point of View
Recognizing and treating skin symptoms in essential thrombocythemia is crucial for patient quality of life.
research Progesterone-Induced Stimulation of Mammary Tumorigenesis Is Due to the Progesterone Metabolite, 5α-Dihydroprogesterone (5αP), and Can Be Suppressed by the 5α-Reductase Inhibitor, Finasteride
Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
research Long-Term Dutasteride Therapy in Men with Benign Prostatic Hyperplasia Alters Glucose and Lipid Profiles and Increases Severity of Erectile Dysfunction
Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
research Finasteride, Not Tamsulosin, Increases Severity of Erectile Dysfunction and Decreases Testosterone Levels in Men With Benign Prostatic Hyperplasia
Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.
research Association Between Androgenetic Alopecia and Coronary Artery Disease in Young Male Patients
Hair loss linked to heart disease in young men.
research A Double-Blind, Placebo-Controlled Study of Inositol in Trichotillomania
Inositol was not more effective than a placebo in treating trichotillomania.
research Chronic Administration of Minoxidil Protects Elastic Fibers and Stimulates Their Neosynthesis with Improvement of the Aorta Mechanics in Mice
Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.
research From Gene to Therapy in Spinal and Bulbar Muscular Atrophy: Are We There Yet?
Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.
research Female Pattern Hair Loss
Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
research Localized Cutaneous Necrosis Associated with the Antiphospholipid Syndrome
A woman with lupus experienced skin death due to a blood clotting disorder after stopping a blood thinner, which healed with treatment.
research Mrp4, A New Mitogen-Regulated Protein/Proliferin Gene; Unique in This Gene Family for Its Expression in the Adult Mouse Tail and Ear
A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.
research Reliability of the Pattern Hair Loss Classifications: A Comparison of the Basic and Specific and Norwood–Hamilton Classifications
The BASP classification is more reliable than the Norwood-Hamilton for classifying hair loss in men and women.
research Recipient-Site Influence in Hair Transplantation
The place where hair is transplanted can change its growth rate and length but not its thickness.
research Pharmacologic Management of Pattern Hair Loss
Treat pattern hair loss with finasteride and topical minoxidil.
research Contact Dermatitis to Phenol-Formaldehyde Resin in Two Plywood Factory Workers
Two plywood factory workers developed contact dermatitis from phenol-formaldehyde resin, a known allergen.
research Androgen Levels and Semen Parameters Among Former Users of Finasteride With Persistent Sexual Adverse Effects
research Applications and Implications of Heparin and Protamine in Tissue Engineering and Regenerative Medicine
Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.
research Association of AR rs6152G/A Gene Polymorphism With Susceptibility to Polycystic Ovary Syndrome in Chinese Women
A certain gene variant may increase the risk of polycystic ovary syndrome in Chinese women.
research Analysis of Genetic Polymorphisms of Steroid 5α-Reductase Type 1 and 2 Genes in Korean Men with Androgenetic Alopecia
Gene differences may affect baldness treatment response in Korean men.
research The History of Hair Transplantation
Hair transplantation has evolved since 1822, with significant advancements by key figures and widespread international growth.
research Caffeic Acid Skin Absorption: Delivery of Microparticles to Hair Follicles
Microparticles help caffeic acid stay longer in hair follicles for better treatment of folliculitis.
research Female Pattern Hair Loss: Beyond an Androgenic Aetiology?
Estrogen and prolactin may play bigger roles in female hair loss than previously thought.
research Antiandrogen Therapy for Androgenetic Alopecia
Antiandrogen therapy helps treat genetic hair loss.
research A Genomic Approach to Susceptibility and Pathogenesis Leads to Identifying Potential Novel Therapeutic Targets in Androgenetic Alopecia
Genomic approach finds new possible treatments for hair loss.
research Hair Restoration in Androgenetic Alopecia: Looking Beyond Minoxidil, Finasteride, and Hair Transplantation
Alternative treatments show promise for hair growth beyond traditional methods.
research A Missense Mutation in the P2RY5 Gene Leading to Autosomal Recessive Woolly Hair in a Syrian Patient
A gene mutation causes woolly hair in a Syrian patient.
research Perforin Expression by Cutaneous Gamma Delta T Cells
Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
research The Impact of 5α-Reductase Inhibitor Use for Male Pattern Hair Loss on Men's Health
Hair loss drugs may cause sexual issues and infertility in men.
research Insights on the Mechanical Behavior of Keratin Fibrils
Keratin's mechanical properties are influenced by hydrogen bonds and secondary structure, and can be improved with the SPD-2 peptide.