November 2025 in “Cancers” This study conducted a meta-analysis and found that men with both frontal and vertex male pattern baldness have a slightly increased risk of developing prostate cancer, though most data was from Caucasian populations and effect modification by genetic variations was not assessed.
January 2025 in “Recent Patents on Anti-Cancer Drug Discovery” In this study, neoadjuvant treatment with durvalumab combined with albumin-bound paclitaxel and carboplatin in patients with driver gene-negative stage III NSCLC showed a 65% objective response rate and was associated with high pathological response rates and improved immune function, with most adverse events being mild.
December 2024 in “Tạp chí Y Dược Huế” This study observed that in 210 infertile women with PCOS, stress significantly negatively impacted quality of life, with infertility-related quality being particularly low, and noted income, BMI, acne, and hirsutism as influential factors.
September 2024 in “Frontiers in Neuroendocrinology” In this review, the researchers reported that 5α-reductase inhibitors demonstrated neuroprotective effects and reduced dyskinesias in animal models of Parkinson's disease, suggesting their potential for repurposing to manage symptoms in men with PD.
August 2024 in “Clinical & experimental pathology” This research highlights significant advancements in forensic DNA phenotyping, enabling predictions of physical traits, ancestry, and age from crime scene DNA, but notes that further research and validation are needed for greater accuracy and reliability.
January 2015 in “Farmatsevtychnyĭ zhurnal” This research discusses the development of a complex tincture for telogen effluvium using nettle, sage, and chestnut leaves, but provides no new clinical results.
January 2012 in “Journal of Investigative Dermatology” Some Greek melanoma patients have gene mutations linked to increased cancer risk, a new color feature helps diagnose melanoma, the incidence of a skin condition in the Netherlands is rare, and a gene possibly affects male-pattern baldness.
In this study, researchers used the CRISPR/Cas9 system to edit the FGF5 gene in Dorper sheep, observing increased density and finer wool, along with changes in cortisol levels and antioxidant enzyme activity linked to hair follicle development.
This study found that treating tobacco roots with specific peptides like Gly, GlyGly, and GlyAsp significantly increased root hair development and influenced gene expression, potentially through an epigenetic mechanism.
612 citations
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February 2004 in “Nature” This study found that the OXI1 gene in Arabidopsis thaliana is vital for activating key protein kinases and is necessary for oxidative burst signal responses like pathogen resistance and root hair growth.
202 citations
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August 2007 in “Biomaterials” This review discusses advancements in artificial skin for wound treatment and reports no new clinical findings; the authors highlight the potential of new biomaterials to enhance future skin replacement therapies.
89 citations
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April 2023 in “Forensic Science International Genetics” This review summarizes advancements in forensic DNA phenotyping for appearance, ancestry, and age prediction from crime scene samples, reporting no new research findings but highlighting areas needing further research and validation.
60 citations
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February 2014 in “Tissue Engineering Part A” This study found that microporous electrospun scaffolds with a 70:30 collagen I to poly(ɛ-caprolactone) ratio significantly accelerated wound closure and dermal regeneration in full-thickness critical-sized skin defects.
53 citations
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October 2011 in “Psychoneuroendocrinology” Finasteride may help improve certain brain function issues linked to dopamine.
52 citations
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October 2010 in “Antiviral Therapy” This review discusses recent advances in monophosphate prodrug strategies for HCV drug discovery, aiming to enhance oral absorption and stability, and reports no new clinical results.
37 citations
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January 2015 in “Journal of Clinical and Experimental Dentistry” This animal study found that both systemic and topical forms of Zizyphus jujuba extract were associated with reduced severity of oral mucositis in golden hamsters treated with 5-fluorouracil.
33 citations
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March 2018 in “Trends in cell biology” This review summarizes evidence suggesting that metabolism actively influences stem cell fate in intestinal and hair follicle stem cells, rather than being a mere environmental byproduct.
31 citations
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September 2020 in “Clinical endocrinology” This review found limited evidence on the effectiveness of different antiandrogens for feminization in transgender women, suggesting cyproterone acetate, leuprolide, and medroxyprogesterone acetate may better suppress testosterone than spironolactone or estradiol alone.
25 citations
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May 2020 in “Progress in Organic Coatings” This study found that bio-based waterborne polyurethanes derived from castor oil may offer effective hair-styling performance without skin irritation and appear to be safer for the environment compared to traditional hair sprays.
23 citations
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December 2013 in “Molecules” This study found that the evodiamine derivative 2-16 exhibited the highest antitumor activity and a broad spectrum of activity against various human cancer cell lines, with improved solubility.
16 citations
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January 2011 in “International Journal of Trichology” This article discusses the principles and considerations of clinical photography for hair disorders in dermatology, reporting no new clinical findings.
11 citations
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July 2021 in “Sustainability” In this study, researchers found that replacing natural aggregates with animal bones and human hair with increased microroughness may improve the mechanical strength and durability of concrete.
10 citations
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January 2022 in “Journal of Research in Pharmacy” In this experimental study on Wistar albino rats, Cotinus coggygria leaf extract demonstrated potential as a treatment for burn-induced skin damage by reducing cytokine levels and promoting tissue healing.
9 citations
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December 2023 in “Journal of Neuroimmune Pharmacology” This study found that systemic administration of NDP-MSH, a melanocortin receptor agonist, provided neuroprotective effects on dopaminergic nigrostriatal neurons in a mouse model of Parkinson's disease, reducing neuroinflammation and suggesting a role for regulatory T cells in these neuroprotective effects.
5 citations
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January 2016 in “Journal of The American Academy of Dermatology” This review discusses inflammatory and medication-related nephrocutaneous disease associations and emphasizes the importance of timely referral to nephrology for early management, but it reports no new clinical results.
5 citations
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May 1994 in “Facial plastic surgery clinics of North America” This article reviews the clinical characterization and potential treatments for androgenetic alopecia, highlighting minoxidil's efficacy in hair regrowth and noting the need for further genetic research; it reports no new clinical results.
4 citations
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February 2021 in “Journal of Pharmaceutical Sciences” This study suggests that the developed PBPK model effectively predicts pharmacokinetic and pharmacodynamic profiles of topical finasteride and minoxidil on the scalp, indicating potential broader applicability for other formulations.
3 citations
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June 2006 in “Expert Review of Dermatology” This review discusses recent advances in hair follicle research, highlighting therapeutic and cosmetic applications, but reports no new study results.
2 citations
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October 2024 in “Pharmaceutics” This study found that reducing the particle size of Tetrastigma hemsleyanum powders improved both dissolution rates and antioxidant activity, suggesting potential benefits for enhancing hepatoprotective effects.
1 citations
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October 2023 in “Pharmaceuticals” In this study, researchers investigated GAGs from the marine invertebrate Microcosmus exasperatus, finding that its polysaccharides possess antitumoral properties without affecting anticoagulant activity. The unique composition shows potential for cancer treatment when combined with existing therapies in future studies.