March 2020 in “Journal of evolution of medical and dental sciences” In this study, the vertex type of male pattern baldness was associated with increased cardiovascular risk factors, suggesting it may serve as a marker for cardiovascular evaluation in men.
July 2019 in “Journal of Dermatology and Dermatologic Surgery” This study found no significant link between headcover use and the severity of male-pattern hair loss among adult males, with age being the only associated factor.
February 2019 in “Case medical research” Using lasers to deliver minoxidil can potentially improve its effectiveness in treating male pattern hair loss.
June 2017 in “IP Indian journal of clinical and experimental dermatology” This study found that using a combination of 10% topical minoxidil, oral finasteride, and microneedling for six months effectively improved male pattern baldness with moderate to excellent responses and high patient satisfaction, without major side effects among the 25 participants.
February 2012 in “European Urology Supplements” Finasteride for hair loss may cause long-lasting sexual side effects in young males.
September 2002 in “Dermatologic Surgery” This study found that the prevalence of male pattern baldness in the Asian population in Bangkok is higher than previously thought, approaching rates seen in Caucasians.
43 citations
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April 2017 in “Experimental Dermatology” This review summarizes the genetic studies on female pattern hair loss, highlighting the lack of clearly identified susceptibility loci and suggesting distinct aetiological differences from male pattern hair loss.
7 citations
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October 2020 in “Journal of Clinical Medicine” In this study, researchers found that overweight and obese women with polycystic ovary syndrome showed adverse changes in glucose metabolism over time, highlighting the importance of early intervention to prevent cardiometabolic diseases.
6 citations
,
December 2023 in “Journal of Clinical Medicine” This review explores the potential link between psoriasis and metabolic syndrome, focusing on how disturbances in growth factors may connect these conditions and contribute to symptoms like keratinocyte proliferation and inflammation.
57 citations
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January 1986 in “The Prostate” This article discusses the role of dihydrotestosterone in human prostatic adenocarcinoma growth and suggests that 6-methyleneprogesterone could be used to inhibit DHT for treating hormone-responsive prostate cancer, without new clinical findings.
53 citations
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August 2014 in “Cochrane library” This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.
51 citations
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August 2015 in “Cochrane library” This systematic review reports that there is currently no evidence supporting methotrexate for maintaining remission in ulcerative colitis; further large-scale trials are needed to assess its efficacy and safety.
14 citations
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August 2009 in “Cancer epidemiology” This study found that AHCC significantly reduced alopecia caused by Ara-C in neonatal rats and improved liver function affected by 6-MP and MTX in mice.
8 citations
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December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses recent advancements made in using mouse models to investigate the genetic complexity and pathogenesis of alopecia areata, emphasizing potential new treatment targets, but it reports no new findings.
6 citations
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June 1994 in “Journal of Animal Science” This study found that none of the depigmenting compounds tested in beef heifers produced a permanent depigmenting effect, though visible depigmentation lasted up to 3 months.
3 citations
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January 2019 in “Journal of Dermatology” This letter to the editor discusses the natural course of epidermolysis bullosa simplex with mottled pigmentation in a Japanese family but does not present new clinical results.
June 2026 in “Frontiers in Bioengineering and Biotechnology” This review outlines the transition from simple hair follicle organoids to immune-competent microphysiological systems, addressing limitations in replicating native hair follicle immune features and discussing their applications in disease modeling and regenerative medicine.
May 2026 in “Journal of Nanobiotechnology” This study found that using a palmitoylated peptide, Pal-MPAPO, delivered through hydrogel microneedles effectively promoted hair regrowth in mice with efficacy comparable to minoxidil, while requiring less frequent application.
32 citations
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August 2019 in “Nature Communications” In this study, researchers found that alkylating chemotherapy causes hair follicle stem cells to lose their regenerative ability by initially triggering proliferation followed by apoptosis, leading to permanent regeneration loss.
2 citations
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November 2023 in “Bioactive materials” The researchers reported that a newly developed ionic liquid-based microemulsion significantly improved the local delivery of copper peptides in mice, enhancing hair growth-related factor activation while offering a safer, non-invasive alternative to existing treatments for hair loss.
January 2023 in “Biocell” The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.
166 citations
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August 2011 in “Dermatologic Surgery” This study found that PRP combined with dalteparin and protamine microparticles may enhance hair growth by increasing hair thickness compared to PRP alone.
1 citations
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June 2013 in “Annals of the Rheumatic Diseases” This study observed that while all DMARD regimens had similar safety profiles, the leflunomide group experienced the most serious side effects leading to therapy discontinuation.
October 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Adding dalteparin and protamine microparticles to platelet-rich plasma can boost hair growth more than using platelet-rich plasma alone.
August 2016 in “Anaplastology” This study reports that controlled release PRP therapy using dalteparin and protamine micro-particles may be effective for hair growth and skin rejuvenation in women.
May 2015 in “Hair transplant forum international” This article contains no research findings; it reports on an online discussion about platelet-rich plasma (PRP) and opinions shared during a conference.
6 citations
,
January 2016 in “Bioorganic & Medicinal Chemistry Letters” This study reported that certain minoxidil conjugates, specifically those with spermine, methylenedianiline, and diaminofluorene, were able to induce differentiation in HL-60 acute myeloid leukemia cells without toxicity at a concentration of 10 μM.
33 citations
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February 2021 in “Journal of Medicinal Chemistry” This study found that novel MPC inhibitor analogues with specific chemical modifications promoted significant hair growth in shaved mice when applied topically.
July 2025 in “Physiological Reviews” This study presents male pattern androgenetic alopecia (mpAGA) as a natural physiological process involving reversible transformation of hair follicles, but notes unresolved links with androgen mechanisms and highlights potential research avenues beyond androgen receptor signaling for treatment exploration.
6 citations
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January 2022 in “Database” This database provides detailed physiological parameters of porcine skin to enhance the MPML MechDermA Model, improving dermal absorption predictions for human studies in the Simcyp Simulator.