11 citations,
June 2019 in “Tissue & Cell” Hair stem cells produce a protein called COL17A1 that plays a key role in their development and is linked to hair thinning and baldness.
May 2024 in “Molecules/Molecules online/Molecules annual” Plant extracts can help prevent hair loss and promote hair growth.
December 2023 in “Aggregate” Scientists are using clumps of special stem cells to improve organ repair.
116 citations,
May 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.
33 citations,
October 2010 in “Journal of Dermatological Science” Hair follicle stem cells are a practical and ethical option for nerve repair in regenerative medicine.
January 2022 in “Stem cell biology and regenerative medicine” Improving dermal papilla cells can help regenerate hair follicles.
37 citations,
January 2009 in “The Journal of Dermatology” Hair follicle stem cells can turn into various cell types and help repair nerves.
6 citations,
July 2007 in “Developmental Dynamics” The molecule Wise is involved in the development of various structures in chick embryos.
50 citations,
February 2007 in “Expert Opinion on Biological Therapy” Hair follicle stem cells could help repair nerves and avoid ethical issues linked to embryonic stem cells.
17 citations,
December 2010 in “Journal of Investigative Dermatology” Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
75 citations,
August 2011 in “Journal of Investigative Dermatology” Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.
150 citations,
May 1993 in “The journal of cell biology/The Journal of cell biology” Mouse Notch is important for determining cell roles in hair follicles.
33 citations,
December 2004 in “Differentiation” Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
205 citations,
April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
January 2004 in “Molecular biotechnology” 949 citations,
January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
130 citations,
January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
25 citations,
May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
13 citations,
October 2002 in “Journal of Investigative Dermatology” The upper half of a human hair follicle can grow a new hair in a mouse, but success is rare.
8 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
51 citations,
May 2019 in “Biomaterials” Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
43 citations,
August 2008 in “Regenerative Medicine” Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
8 citations,
January 2017 in “Methods in molecular biology” Stem cells rearrangement regenerates functional hair follicles, potentially treating hair loss.
29 citations,
December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
16 citations,
January 2007 in “Dermatology” Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.
68 citations,
December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
160 citations,
January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
53 citations,
October 2012 in “The FASEB Journal” Bimatoprost, a glaucoma medication, may also help treat hair loss.
1 citations,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
May 2023 in “Frontiers in Cell and Developmental Biology” The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.