research Aberrant Wnt Signaling Induces Comedo-Like Changes in the Murine Upper Hair Follicle
Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
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research Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding
Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
research Impaired Differentiation Potential of CD34-Positive Cells Derived from Mouse Hair Follicles After Long-Term Culture
Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.
research GDNF Promotes Hair Formation and Cutaneous Wound Healing by Targeting Bulge Stem Cells
GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
research Bioengineered Skin Organoids: From Development to Applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research IL-36α Promoted Wound-Induced Hair Follicle Neogenesis via Hair Follicle Stem/Progenitor Cell Proliferation
IL-36α helps grow new hair follicles and speeds up wound healing.
research Epidermal Stem Cell Lineages: Roles in Skin Integrity, Stress Response, and Disease
Epidermal stem cells are crucial for skin health and problems with them can cause issues like poor wound healing, cancer, and aging.
research Development and Homeostasis of the Sebaceous Gland
The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
research Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche
Different types of stem cells and their environments are key to skin repair and maintenance.
research Generation of Folliculogenic Human Epithelial Stem Cells from Induced Pluripotent Stem Cells
Scientists created stem cells that can grow hair and skin.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research Vibrissa Hair Bulge Houses Two Populations of Skin Epithelial Stem Cells Distinct by Their Keratin Profile
There are two types of stem cells in rodent hair follicles, each with different keratin proteins.
research Engineered Skin Substitute Regenerates Skin with Hair Follicle Formation
The engineered skin substitute helped grow skin with hair on mice.
research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Vitamin A Resolves Lineage Plasticity to Orchestrate Stem Cell Lineage Choices
Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.
research Restoration of Hair-Inductive Activity of Cultured Human Follicular Keratinocytes by Co-Culturing with Dermal Papilla Cells
Growing hair cells with dermal cells can potentially treat hair loss.
research Endocannabinoids Limit Excessive Mast Cell Maturation And Activation In Human Skin
Endocannabinoids help control mast cell activity in human skin.
research Elevated Ornithine Decarboxylase Activity Promotes Skin Tumorigenesis by Stimulating the Recruitment of Bulge Stem Cells but Not via Toxic Polyamine Catabolic Metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research Mechanical Stimulation of Human Hair Follicle Outer Root Sheath Cultures Activates Adjacent Sensory Neurons
Touching hair can activate nearby nerve cells through signals from the hair's outer layer.
research Adult Epidermal Notch Activity Induces Dermal Accumulation of T Cells and Neural Crest Derivatives Through Upregulation of Jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation
Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
research Wound Healing and Skin Regeneration
Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research SOX2 in the Skin: Roles in Biology and Pathology
SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research MOF-Mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions by Controlling Gene Promoters
MOF controls skin development by regulating genes for mitochondria and cilia.
research The Effects of 3-Hydroxy of Kaempferol on Interfollicular Epidermal Stem Cell Fate
Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.
research Dermal Papilla Cells: From Basic Research to Translational Applications
Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
research The Role and Prospects of Mesenchymal Stem Cells in Skin Repair and Regeneration
Mesenchymal stem cells show promise for effective skin repair and regeneration.