A low dose of rapamycin increases inner ear hair cell creation by boosting SOX2+ cell numbers.
[object Object] 129 citations,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
21 citations,
June 2018 in “Current Opinion in Genetics & Development” Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
291 citations,
April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
January 2022 in “Stem cell biology and regenerative medicine” New biofabrication technologies could lead to treatments for hair loss.
47 citations,
June 2013 in “Biology of blood and marrow transplantation” Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.
[object Object] 17 citations,
March 2012 in “The Journal of Pathology” In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.
53 citations,
September 2020 in “Stem Cell Research & Therapy” New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
July 2023 in “Biomolecules” The new "whisker follicle microinjection assay" can test how different biomolecules affect hair growth and color.
8 citations,
January 2019 in “Experimental Dermatology” The 3D skin model is better for hair growth research and testing treatments.
50 citations,
July 2021 in “Nature Communications” The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
31 citations,
April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
6 citations,
December 2021 in “Scientific Reports” Inhibiting class I HDACs helps maintain hair growth ability in skin cells.
December 2024 in “Highlights in Science Engineering and Technology” Stem cells show promise for hair regrowth, but challenges remain.
May 2022 in “Gastroenterology” Targeting NETs may help reduce fibrosis in Crohn's disease.
April 2021 in “Journal of Investigative Dermatology” The research found genes that may protect certain scalp cells from hair loss.
8 citations,
April 2019 in “ACS Biomaterials Science & Engineering” The new SIS-PEG sponge is a promising material for skin regeneration and hair growth.
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists can now create skin with hair by reprogramming cells in wounds.
42 citations,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
January 2025 in “Cellular and Molecular Life Sciences” BMP4 helps stem cells turn into pigment-producing cells, affecting hair color and growth.
February 2024 in “International Journal of Biological Macromolecules” The study created a new type of microsphere that effectively regrows hair.
16 citations,
July 2023 in “Acta biomaterialia” The study developed a new way to create hair-growing tissue that can help regenerate hair follicles and control hair growth direction.
6 citations,
August 1991 in “Pediatric Clinics of North America” The document concludes that various hair and scalp disorders in children have specific treatments and proper diagnosis is essential.
721 citations,
October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
16 citations,
August 1992 in “Archives of dermatological research” Lab-grown nail cells show characteristics similar to natural nail and hair.
11 citations,
July 2016 in “Current Opinion in Cell Biology” New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.
146 citations,
May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
124 citations,
February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
51 citations,
November 2013 in “Drug Discovery Today” Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
14 citations,
June 2021 in “Expert Opinion on Therapeutic Patents” New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.