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Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.

The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.

Mouse models help understand alopecia areata and find treatments.

CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.

Researchers improved mouse skin cell culture methods and created a similar immortal cell line, but need to clarify their methods and benefits.

The C3H/HeJ mouse model is useful for studying and testing treatments for alopecia areata.

The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.

The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.

Scientists improved how to grow mouse skin cells in the lab and created a long-lasting cell line, but didn't fully explain its advantages or compare it to normal cells.

The review suggested the study needed to clarify its purpose, compare with non-immortalized cells, and provide more details on methods.

Certain skin proteins can form anchoring structures without the protein AMACO.

Disrupted stem cell signals in hairpoor mice cause hair loss.

PGD2 stops hair growth and is higher in bald men with AGA.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.

The E2 protein affects gene activity in hair follicles of mice.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.

The Hairless gene is crucial for hair cell development, affecting whether skin cells become hair or skin and oil gland cells.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.

VDR regulation varies by tissue and is crucial for its biological functions.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.