research Twist2 Contributes to Skin Regeneration and Hair Follicle Formation in Mouse Fetuses
Twist2 is essential for proper skin healing and hair growth in developing mice.
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research Hair Follicle Regeneration Using Grafted Rodent and Human Cells
Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
research Twist2 Contributes to Skin Regeneration and Hair Follicle Formation in Mouse Fetuses
Twist2 is essential for scarless skin healing and hair growth in mouse fetuses.
research Inducible Deletion of Epidermal Dicer and Drosha Reveals Multiple Functions for miRNAs in Postnatal Skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
research Azelaic Acid Stimulates Catalase Activation and Promotes Hair Growth Through Upregulation of Gli1 and Gli2 mRNA and Shh Protein
Azelaic acid helps protect hair cells from UV damage and encourages hair growth by increasing certain gene expressions and proteins.
research Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research Decision Letter: Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
research Functional Hair Follicle Regeneration by the Rearrangement of Stem Cells
Stem cells rearrangement regenerates functional hair follicles, potentially treating hair loss.
research Mapping the Molecular and Structural Specialization of the Skin Basement Membrane for Inter-Tissue Interactions
The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
research Bimatoprost Promotes Hair Growth of Reconstructed Hair Follicles in Mice Through Activation of the Wnt/β-Catenin Signaling Pathway
Bimatoprost helps mouse hair grow by turning on a specific growth pathway.
research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research The Circadian Molecular Clock Creates Epidermal Stem Cell Heterogeneity
The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
research Epidermal/Dermal Separation Techniques and Analysis of Cell Populations in Human Skin Sheets
Choosing the right method to separate skin layers is key for good skin cell research.
research Expansion of Specialized Epidermis Induced by Hormonal State and Mechanical Strain
Hormones and stretching both needed for nipple area skin growth in mice.
research Therapeutic Potential of Patient iPSC-Derived Melanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research GDNF Neurotrophic Factor Signaling Determines the Fate of Dermal Fibroblasts in Wound-Induced Hair Neogenesis and Skin Regeneration
GDNF signaling helps in hair growth and skin healing after a wound.
research Evidence That Mirex Promotes a Unique Population of Epidermal Cells That Cannot Be Distinguished by Their Mutant Ha-ras Genotype
Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.
research Molecular Principles of Hair Follicle Induction and Morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research DNMT1-Mediated Methylation Inhibits MicroRNA-214-3p and Promotes Hair Follicle Stem Cell Differentiation Into Adipogenic Lineages
DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
research Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Skin stem cells in hair follicles are important for touch sensation.
research Expansion Culture of Hair Follicle Stem Cells Through Uniform Aggregation in Microwell Array Devices
The new microwell device helps grow more hair stem cells that can regenerate hair.
research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Fat-related cells are important for initiating hair growth.
research Bioengineered Polyester Nanoparticles for the Synergistic Treatment of Androgenic Alopecia via the Suppression of 5α-Reductase and Knockdown of Androgen Receptor
Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.
research In Vivo Reprogramming of Wound-Resident Cells Generates Skin with Hair
Scientists can now create skin with hair by reprogramming cells in wounds.
research Reawakening GDNF's Regenerative Past in Mice and Humans
Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research Stem Cell Heterogeneity and Plasticity in Epithelia
Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
research Scratching the Surface of Skin Development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.