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Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.

An imbalanced gut and lack of biotin can cause hair loss in mice.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

HIV can cause unusual and severe skin problems that are hard to treat.

The document suggests a possible link between Crohn's disease and Johne's disease and calls for more research.

Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.