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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Retinoic acid affects male and female muscle energy use and function differently.

Androgen use may increase the risk of stroke, but more research is needed.

Ivacaftor can protect against noise-induced hearing loss by reducing oxidative stress.

Taking too much vitamin E caused a young man's blood clotting problems, which improved after he stopped the vitamin E and got treatment.

Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.

Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Miracle fruit seed oil significantly reduces hair breakage in women with damaged hair.

Hair follicle stem cells can become nerve cells using specific treatments.

HAP stem cells can repair nerves, grow hair follicle nerves, and become heart muscle cells, making them useful for regenerative medicine.

Healthy lifestyle changes can significantly improve skin health as you age.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Patients with alopecia areata have higher oxidative stress and lower antioxidant levels.

Finasteride may help treat autism by reducing inflammation and oxidative stress.

Some traditional Chinese medicines may have anti-aging benefits and could help with hair growth, but more research is needed.

Non-surgical treatments like thread lifts, PRP therapy, HIFU, and radiofrequency effectively rejuvenate and tighten facial skin.

VKHD and sarcoidosis may share a common cause.

Early diagnosis and hormone therapy can significantly improve outcomes for post-partum pituitary insufficiency in resource-limited settings.

Mild oxidative stress can prevent hair loss from chemotherapy.

Undiagnosed lupus can cause severe complications after epidural anesthesia, leading to muscle weakness and potentially death.

The document outlines steps for moving fat from one body part to another.

Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.

Exposure to certain metals may worsen attention-related behaviors in adolescents, with stronger effects in females.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

Too much selenium can cause hair loss and nail problems.

CRABP2 helps increase the growth of cells important for hair growth by activating a specific growth pathway.

Exosomes could be a promising way to help repair skin and treat skin disorders.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.