research Behavioral Characterization of Vitamin D Receptor Knockout Mice
Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.
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research Neuropharmacological Profile of Eclipta Alba (Linn.) Hassk
Eclipta alba extract improved learning, memory, and stress-related ulcers in rats without affecting movement or causing anxiety.
research Flavonoid 4,4'-Dimethoxychalcone Selectively Eliminates Senescent Cells Via Activating Ferritinophagy
The substance DMC helps get rid of aging cells by triggering a process that causes cell death, which could treat age-related diseases.
research Dietary Intake in Subjects with Early Psychosis: Is There a Relationship with Clinical Subtype or Antipsychotic Treatment?
People with early psychosis eat more calories, saturated fat, and sugar, and the drug olanzapine may lead to eating even more calories.
research Sodium Valproate: Doctor Jekyll and Mister Hyde
Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.
research Physiological Functions of PP2A: Lessons from Genetically Modified Mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
research Ethnopharmacological Significance of Eclipta Alba (L.) Hassk. (Asteraceae)
Eclipta alba has many health benefits and contains compounds with potential for drug development.
research The 5α-Reductase Inhibitor Finasteride Exerts Neuroprotection Against Ischemic Brain Injury in Aged Male Rats
Finasteride helps protect brain in old male rats.
research Pantothenic Acid Promotes Dermal Papilla Cell Proliferation in Hair Follicles of American Minks via Inhibitor of DNA Binding 3/Notch Signaling Pathway
Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.
research Management of Recurrent Ischemic Priapism: A Complex Condition with Devastating Consequences
Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.
research Effect of Ethanol Adiantum Capillus-Veneris Extract in Experimental Models of Anxiety and Depression
Maidenhair fern extract reduced anxiety and depression in rats and may work due to its antioxidant and anti-inflammatory properties.
research MendelVar: Gene Prioritization at GWAS Loci Using Phenotypic Enrichment of Mendelian Disease Genes
MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.
research A Review on Phytopharmacological Significance of Eclipta Alba
Eclipta alba has many health benefits and potential for medical and nutritional use.
research Analysis of Androgen Receptor Expression and Activity in the Mouse Brain
Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.
research Uncombable Hair Syndrome and Beyond
Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.
research New Intranasal and Injectable Gene Therapy for Healthy Life Extension
Gene therapy in mice increased lifespan and improved health without causing cancer.
research Main Plenary Sessions: Summaries of Papers
UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.
research Long-Term Administration of Triterpenoids From Ganoderma Lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice
Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.
research Frizzled Receptors in Development and Disease
Frizzled receptors are essential for various body development processes and maintaining certain body functions.
research Therapeutic, Prophylactic, and Functional Use of Probiotics: A Current Perspective
Probiotics show promise for health benefits but need more research to understand how they work.
research Overexpression of the 18 kDa Translocator Protein (TSPO) in the Hippocampal Dentate Gyrus Produced Anxiolytic and Antidepressant-Like Behavioral Effects
Increasing TSPO in the brain reduces anxiety and depression.
research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and Delta-Subunit-Containing Gamma-Aminobutyric Acid A Receptors
14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
research Expanding the Phenotype: Four New Cases and Hope for Treatment in Bachmann-Bupp Syndrome
Four new cases of Bachmann-Bupp syndrome suggest potential for targeted treatment.
research Sex Differences in Animal Models of Sodium Valproate-Induced Autism in Postnatal BALB/c Mice: Whole-Brain Histoarchitecture and 5-HT2A Receptor Biomarker Evidence
Male mice are more susceptible to autism-like changes from valproic acid than female mice.
research From Structural Resilience to Cell Specification: Intermediate Filaments as Regulators of Cell Fate
Intermediate filaments are crucial for cell differentiation and stem cell function.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research Dermatologic Signs and Symptoms of Substance Abuse
Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.
research DPP-4 Inhibition with Linagliptin Ameliorates the Progression of Premature Aging in Klotho−/− Mice
Linagliptin slows down premature aging in certain mice.
research Hormone-Dependent Medial Preoptic, Lumbar Spinal Cord, and Autonomic Coordination Supporting Male Sexual Behaviors
Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
research Cleave But Not Leave: Astrotactin Proteins in Development and Disease
Astrotactin proteins are important for brain and skin development and are linked to several neurodevelopmental disorders.