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The document concludes that more research is needed to understand how to treat muscle pain with drugs.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

HIV can cause various nail and hair disorders, important for early diagnosis and treatment.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Androgens prevent hair growth by changing Wnt signals in cells.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

Spironolactone plus finasteride reduces hirsutism more effectively.

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Skin symptoms are important for diagnosing and managing juvenile-onset systemic lupus erythematosus and usually get better with treatment.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.