26 citations
,
January 2019 in “Experimental Dermatology” This study developed an in vitro system to analyze human skin progenitor cells' ability to form hair peg-like structures, providing insights for engineering hair follicle organoids.
19 citations
,
April 2015 in “Developmental Dynamics” This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.
10 citations
,
April 2013 in “Journal of Investigative Dermatology” This study found that ovine dermal papilla cells exhibit robust aggregation in culture, offering a model to investigate the regulation of hair follicle dermal papilla size.
7 citations
,
January 2013 in “BioMed research international” This review highlights surprising similarities between hair follicles and antler units, suggesting that a comparative study of their biology could benefit understanding in both areas without presenting new empirical findings.
5 citations
,
January 1993 in “PubMed” In this study, retinoic acid treatments induced glandular and feather formation in embryos by altering positional values and activating specific retinoic acid nuclear receptor gene expression.
1 citations
,
January 2024 in “International journal of molecular sciences” This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This source establishes prior art for treating androgenic alopecia and sexual dysfunction by restoring gap-junction-mediated connectivity in tissue networks, highlighting a mechanism independent of commonly targeted pathways.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This document outlines a defensive publication on restoring gap-junction-mediated morphogenetic field connectivity to address disorders of tissue function, with no new clinical results reported.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This document, authored by Jack Schaffer, establishes prior art for methods aimed at treating disorders related to tissue function by restoring bioelectric communication among cells, preceding specific applications for conditions like androgenic alopecia and age-related sexual dysfunction.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This source discusses defensive publication regarding methods to treat androgenic alopecia and sexual dysfunction by restoring gap-junction-mediated connectivity, highlighting a unique mechanism independent of membrane voltage and not targeted by current treatments.
This study found that hyaluronic acid increased the size of hair follicle germ-like aggregates and the number of proliferative cells but did not maintain specific markers during the process.
September 2017 in “Journal of Investigative Dermatology” This study found that hyaluronic acid increased the size and cell proliferation of mixed aggregates in a 3D culture model, indicating its role in human hair follicle germ-like structure formation without enhancing dermal papilla cell markers.
May 2012 in “International Journal of Dermatology and Venereology” This article reviews the morphogenesis and cycling of hair follicles and the complex signaling pathways involved, without reporting new experimental results.
57 citations
,
August 1997 in “Microscopy Research and Technique” This review discusses novel molecular techniques in skin appendage research and summarizes the distribution of key molecules, but it reports no new experimental results.
56 citations
,
January 1970 in “Cell and Tissue Research” 46 citations
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August 2012 in “Experimental Dermatology” In this study, engineered skin substitutes containing murine dermal papilla cells developed hair follicle-like structures when grafted onto mice, suggesting a model for generating chimeric hair.
46 citations
,
January 1991 in “Tissue and Cell” This study observed that during male silkmoth development, trichogen cells in olfactory sensilla undergo significant membrane recycling, contributing to sensillum structure formation in a precisely timed series of stages.
45 citations
,
December 1991 in “Annals of the New York Academy of Sciences” This study reports that different adhesion molecules play distinct roles in the morphogenesis of feathers and hair, influencing processes such as mesenchymal condensation, epithelial folding, and cell death.
43 citations
,
November 2018 in “Nature Communications” This genome-wide association study identified 20 genetic signals at 15 risk loci related to severe acne, revealing new insights into its genetic predisposition, particularly affecting skin structure and maintenance.
21 citations
,
May 2022 in “Frontiers in Cell and Developmental Biology” This review covers the structure, development, cycle, and molecular regulation of hair follicles but does not report new results, aiming to offer insights for addressing hair follicle-related diseases.
21 citations
,
November 2010 in “Journal of molecular medicine” This study found that deleting FoxN1 in specific thymic epithelial cells disrupted the 3D thymic structure and led to age-dependent formation of 2D epithelial cysts, highlighting FoxN1's critical role in thymic morphogenesis.
14 citations
,
January 1988 4 citations
,
October 2004 in “Humana Press eBooks” This chapter reports an organ culture method that permits mouse embryonic skin tissues to develop similarly to in vivo conditions, revealing that epidermal growth factor inhibits hair follicle formation.
3 citations
,
April 2014 in “Anatomy Research International” This study detailed the developmental stages of the buffalo mammary gland during prenatal growth, identifying key morphological features at various gestation lengths.
1 citations
,
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study provided a detailed molecular profile of Cashmere goat hair follicle development using single-cell RNA sequencing, revealing unique cell populations and conserved developmental programs compared to mouse models.
November 2025 in “Journal of Investigative Dermatology” Mesenchymal stiffness affects sweat gland cell development.
January 2001 in “Biomedical Research” This study observed that PAD type III and trichohyalin are expressed earlier than their deiminated form during the first and second hair cycles in rat hair follicles, indicating a potential additional factor is involved in triggering deimination.
300 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” This review discusses mesenchymal–epithelial interactions in hair follicle development and cycling, highlighting recent insights without reporting new experimental results.
223 citations
,
January 2014 in “International Journal of Molecular Sciences” This article reviews the complex signaling pathways between epithelial and mesenchymal cells crucial for hair follicle morphogenesis, highlighting the Wnt pathway's role as a master regulator without reporting new experimental findings.
204 citations
,
October 1999 in “EMBO journal” This study found that overexpression of activin in transgenic mice led to enhanced granulation tissue formation after skin injury due to changes in keratinocyte proliferation and differentiation.