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210-240 / 255 resultsresearch The L412F Variant of Toll-Like Receptor 3 Is Associated with Cutaneous Candidiasis, Increased Susceptibility to Cytomegalovirus, and Autoimmunity
The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.
research Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress During Hair Cycling
Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
research The Circular RNA circNlgn Mediates Doxorubicin-Induced Cardiac Remodeling and Fibrosis
A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.
![Part II: Common Questions and Misconceptions About Creatine Supplementation: What Does the Scientific Evidence Really Show?](/images/research/2836d47d-f11a-42a9-8361-a2701e0d8ef5/small/40921.jpg)
research Part II: Common Questions and Misconceptions About Creatine Supplementation: What Does the Scientific Evidence Really Show?
Creatine monohydrate is safe and effective for muscle recovery and performance, especially for those with low creatine levels.
![An EGFP-Col4a2 Mouse Model Reveals Basement Membrane Dynamics Underlying Hair Follicle Morphogenesis](/images/research/e13edaa7-3fd6-4f08-965e-8405cd8741d3/small/40742.jpg)
research An EGFP-Col4a2 Mouse Model Reveals Basement Membrane Dynamics Underlying Hair Follicle Morphogenesis
Basement membrane changes are crucial for hair follicle development.
![Author Response: Lhx2 as a Progenitor-Intrinsic Modulator of Sonic Hedgehog Signaling During Early Retinal Neurogenesis](/images/research/2faf59f3-c2b7-465b-8f04-f742e8ad17cb/small/34521.jpg)
research Author Response: Lhx2 as a Progenitor-Intrinsic Modulator of Sonic Hedgehog Signaling During Early Retinal Neurogenesis
Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.
research The Role of Rare Variants in Male-Pattern Hair Loss: Analysis of Whole Exome Sequencing Data in the UK Biobank
Rare genetic variants in 125 genes are linked to male-pattern hair loss.
![The Effect of Topical Minoxidil Treatment on Hair Follicular Growth of Neonatal Hairless Descendants of Mexican Hairless Dogs](/images/research/167471c1-3e82-407c-8eee-f780198856af/small/12532.jpg)
research The Effect of Topical Minoxidil Treatment on Hair Follicular Growth of Neonatal Hairless Descendants of Mexican Hairless Dogs
Minoxidil treatment can stimulate hair growth in hairless puppies if applied early.
![Challenges in the Diagnosis of Simple-Virilizing Congenital Adrenal Hyperplasia: A Case Report](/images/research/5df0ee7d-d7e7-436b-a8aa-9dd29c45b955/small/32698.jpg)
research Challenges in the Diagnosis of Simple-Virilizing Congenital Adrenal Hyperplasia: A Case Report
Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.
research Genetic Hair and Nail Disorders
Recent progress has been made in understanding inherited hair and nail disorders.
![An Epistatic Effect of KRT25 on SP6 Is Involved in Curly Coat in Horses](/images/research/018e2c28-dbce-4df5-b067-39601d158806/small/12740.jpg)
research An Epistatic Effect of KRT25 on SP6 Is Involved in Curly Coat in Horses
The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.
research The Chemokine SDF-1/CXCL12 Regulates the Migration of Melanocyte Progenitors in Mouse Hair Follicles
SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
![Clonal Multipotency and Effect of Long-Term In Vitro Expansion on Differentiation Potential of Human Hair Follicle Derived Mesenchymal Stem Cells](/images/research/77286d6f-ecb2-4917-a21a-a5dc25b8b3b6/small/21904.jpg)
research Clonal Multipotency and Effect of Long-Term In Vitro Expansion on Differentiation Potential of Human Hair Follicle Derived Mesenchymal Stem Cells
Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.
research Epithelial Expression of the Hormone Leptin by Bovine Skin
Cattle skin has leptin which might control skin and hair growth.
![Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor](/images/research/b82073c2-9874-4f46-9f73-802e51715ec6/small/23067.jpg)
research Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor
Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
![Mechanical and Biological Properties of Keratose Biomaterials](/images/research/960ce911-679c-4472-94e0-dcefb3ae43d1/small/29296.jpg)
research Mechanical and Biological Properties of Keratose Biomaterials
Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
![Association of Insulin-Like Growth Factor 2 Apa1 A820G Gene (rs680) Polymorphism with Polycystic Ovarian Syndrome](/images/research/50f2fa30-5a96-401b-adfd-85e8d3ad3415/small/13981.jpg)
research Association of Insulin-Like Growth Factor 2 Apa1 A820G Gene (rs680) Polymorphism with Polycystic Ovarian Syndrome
A certain gene variation is linked to a higher risk of polycystic ovarian syndrome in South Indian women.
![Medical Management Options for Hair Loss](/images/research/a3e13dec-68a3-4b9b-93a7-ab8ba9468537/small/14755.jpg)
research Medical Management Options for Hair Loss
The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.
![Minoxidil: Mechanisms of Action on Hair Growth](/images/research/db5166e6-b6c4-45e9-bbaf-d0900999eaa5/small/2524.jpg)
research Minoxidil: Mechanisms of Action on Hair Growth
Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
![Molecular Signaling in Feather Morphogenesis](/images/research/688c12a5-018f-4851-abe7-93f0f1ba1862/small/35663.jpg)
research Molecular Signaling in Feather Morphogenesis
Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.
![Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo](/images/research/0caf5677-a152-4a22-9687-0393934d2eff/small/27222.jpg)
research Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo
Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
![Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells](/images/research/5c7d7553-0ba7-44c1-9520-84314f76d547/small/20441.jpg)
research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
![Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice](/images/research/563127f1-14e0-40d7-8c67-d1ef187383a5/small/34357.jpg)
research Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice
A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
![Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle](/images/research/394ba1c8-c5be-4d76-8c43-559bf7ffc8f0/small/14852.jpg)
research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle
Ephrins slow down skin and hair follicle cell growth.
![Hypertrichosis Induced by Latanoprost](/images/research/86dff265-7afc-4640-bc63-d5c8997ceece/small/15472.jpg)
research Hypertrichosis Induced by Latanoprost
Latanoprost, a glaucoma medication, caused excessive eyelid hair growth in many patients.
![Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1](/images/research/7de5a316-1f7f-480b-9a73-a6046fe860ca/small/29670.jpg)
research Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1
IGF-1 increases whisker growth in transgenic mice.
![Platelet-Rich Fibrin Matrix for Androgenetic Alopecia](/images/research/ec697490-bfdf-4f54-9751-8fa6beb765c4/small/3439.jpg)
research Platelet-Rich Fibrin Matrix for Androgenetic Alopecia
PRFM may help treat hair loss, especially in mild cases.
![Alopecia in Congenital Hidrotic Ectodermal Dysplasia Responding to Treatment with a Combination of Topical Minoxidil and Tretinoin](/images/research/e48e8fd0-0a10-440a-85e1-798a4abea998/small/2851.jpg)
research Alopecia in Congenital Hidrotic Ectodermal Dysplasia Responding to Treatment with a Combination of Topical Minoxidil and Tretinoin
Hair loss in Clouston's syndrome improved with minoxidil and tretinoin treatment.
![Lasers, Microneedling, and Platelet-Rich Plasma for Skin Rejuvenation and Repair](/images/research/6276190f-fc50-4cb8-bccb-06c59d0cdf42/small/17821.jpg)
research Lasers, Microneedling, and Platelet-Rich Plasma for Skin Rejuvenation and Repair
Lasers, microneedling, and PRP improve skin rejuvenation and repair, with PRP enhancing the effects when combined with other treatments.