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This review discusses the design and advances of lipid–polymer hybrid nanoparticles as promising delivery systems for genome editing strategies, highlighting their potential in biomedical applications.

This study found that ZnO nanoparticles in topical skin products do not penetrate beyond the outer skin layers in humans, suggesting minimal safety concerns for subdermal absorption.

This review discusses various nanoparticles and nanoemulsions being investigated for transdermal drug delivery and reports no clinical results; it highlights potential applications in treating alopecia, wound healing, psoriasis, and melanoma.

This study developed minoxidil sulphate-loaded chitosan nanoparticles that doubled drug delivery to hair follicles in vitro compared to a control solution, suggesting potential for improved alopecia treatment.

This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.

This study found that nano-sized minoxidil formulations significantly increased skin penetration and follicular drug delivery for alopecia areata treatment, compared to conventional ethanol-based solutions, and demonstrated effective controlled release over six hours.

This study found that a phytosomal delivery system improved the bioavailability of Cuscuta reflexa extract compared to the plain extract, suggesting enhanced potential for this formulation.

This animal study found that biscuits fortified with zinc oxide nanoparticles improved growth, appetite, and hair growth in zinc-deficient rats more effectively than traditional zinc forms, without apparent toxicity.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

This study found that finasteride- and minoxidil-loaded nanoparticles in a gel improved skin permeability and drug retention, suggesting a promising approach for topical alopecia treatment with reduced dosing frequency and side effects.

This study found that pretreatment combining maceration with press-shear force and moist heat significantly increased the total phenolic and flavonoid contents in galactagogue herbs like banana inflorescences and Thai ginger.

This review discusses the benefits and applications of microsponges delivery systems in drug delivery, particularly for topical treatments, and reports no new clinical findings.

This review examines nanozymes as promising tools for cancer diagnosis and therapy due to their enzyme-mimicking catalytic properties and highlights their challenges, including biosafety and clinical translation, alongside potential improvements through biomimetic designs, particularly utilizing exosome-based strategies for targeted delivery to tumors.

This study investigated spanlastic nanovascular drug delivery systems and found that they can effectively enhance the transport and continuous release of medicines with small particle size, low polydispersity index, and satisfactory entrapment efficiency, showing potential as carriers for drug delivery.

The researchers evaluated scientific data on the usage and pharmaceutical applications of ascorbic acid derivatives, such as ascorbyl-6-palmitate and ascorbyl-2-glucoside, highlighting their development into stable delivery platforms to overcome ascorbic acid's instability and formulation challenges.

This review discusses how nanotechnology can enhance the efficacy of hair care products by improving the delivery and benefits of active substances and offers insights into potential risks.

This literature review discusses the challenges and potential strategies for creating fully functional hair follicles capable of active cycling, emphasizing the molecular mechanisms, signaling pathways, and innovative regenerative techniques, such as hair micropatterning and three-dimensional printing, crucial for optimizing hair follicle regeneration.

This study reported a green synthesis method for copper oxide nanoparticles using pumpkin seed extract, achieving significant antibacterial activity against Bacillus subtilis and moderate cytotoxic effects against certain cancer cell lines, indicating potential biomedical applications for these eco-friendly nanomaterials.

In this study, peptide-based nanoparticles were successfully used to deliver the CRISPR-Cas9 system into cancer cells, effectively targeting and editing KRAS mutations, suggesting promising therapeutic potential for cancer treatment.

This review updates on the development of liposomal carriers for delivering growth factors to improve tissue regeneration and highlights recent efforts to enhance their stability and retention in tissues.

This study demonstrated that finasteride-loaded PLGA microspheres created using a novel microfluidic device exhibit extended drug release in beagle dogs, with modifications allowing for release up to 3 months.

This study demonstrated that human hair can be coated with Fe3O4 nanoparticles, allowing it to be oriented and moved by a magnetic field, which may enhance drug delivery and hair care applications.

This review highlights silk fibroin and its nanocomposites as promising materials for wound healing, addressing challenges in chronic wound treatment, especially in developing countries, and examines the obstacles in bringing silk-based products to market.

In this animal study, oral administration of wedelolactone significantly improved bone mineral density and reduced osteoclast numbers in a model of particle-induced osteolysis, suggesting potential as a treatment option.

This study developed caffeine-loaded nanoparticles coated with ultradeformable liposomes for better hair follicle delivery, showing non-cytotoxicity and potential to reduce oxidative stress in DHT-damaged cells, suggesting an alternative treatment for androgenetic alopecia.

This study found that low massage frequencies like 4.2 Hz enhance nanoparticle penetration into hair follicles more effectively than higher frequencies, indicating potential applications in therapeutic and cosmetic delivery.

This review paper highlights the development and application of organic and biogenic nanocarriers for delivering bioactives, focusing on eco-friendly and sustainable nanotechnology strategies while addressing challenges like toxicity and paving the way for future innovations in green solution approaches.

This study found that chitosan nanoparticle-encapsulated Cordyceps militaris significantly reduced inflammation and oxidative stress in particulate matter-exposed mice, suggesting potential use for managing lung inflammation.

This study used cryoelectron microscopy to unveil the structure of LPA-bound human LPAR6, revealing unique ligand binding and recognition modes distinct from LPAR1, which may aid in designing targeted compounds for hair loss and cancer.

This review discusses the role of extracellular vesicles in psoriasis pathogenesis and their potential as therapeutic agents or drug delivery systems, but it reports no new clinical findings.