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Targeting the skin's endocannabinoid system could help treat skin disorders.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Apoptosis is crucial for healthy skin and treating skin diseases.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.

TGF-β2 plays a key role in human hair growth and development.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.