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TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Lowering testosterone speeds up wound healing in male mice.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Targeting the skin's endocannabinoid system could help treat skin disorders.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.