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The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.

Probiotic bacteria improved skin and hair health in aged mice.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Fat cells in the skin help start healing and form important repair cells after injury.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Targeting hair follicles can improve skin treatments and reduce side effects.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Green tea component EGCG could potentially promote human hair growth.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.