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TNF-alpha inhibitors can cause various immune-related skin issues.

New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Rat hair-follicle stem cells can become heart cells with specific supplements.

Taking vitamin C and vitamin E twice a day can help prevent sunburn and DNA damage from UVB exposure.

In 2019, dermatology and venereology improved skin cancer imaging, advanced in treating skin conditions like psoriasis, and explored the skin microbiome's role in diseases.

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

The exam tested knowledge on various skin-related topics for CME credit.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Apoptosis is essential for human skin development and forming a functional epidermis.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.