research MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata
A substance called miR-1246 may help treat severe hair loss by reducing certain immune cell activities.
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research Long-Acting Microneedle Formulations
Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
research Role of FGFR2-Signaling in the Pathogenesis of Acne
Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.
research Lack of Efficacy of Topical Latanoprost and Bimatoprost Ophthalmic Solutions in Promoting Eyelash Growth in Patients with Alopecia Areata
Topical latanoprost and bimatoprost eye solutions don't help eyelash growth in people with alopecia areata.
research Stem Cell Apoptosis in HIV-1 Alopecia
HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
research Topical Minoxidil in Alopecia Areata: No Effect on the Perifollicular Lymphoid Infiltration
Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.
research CD44 Expression in Alopecia Areata and Androgenetic Alopecia
No CD44 in alopecia areata, present in normal and androgenetic alopecia.
research Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database
Biologics for severe asthma have known side effects, but some new risks need more study.
research Alopecia Universalis: An Extremely Rare but Probable Adverse Effect of Adalimumab
Adalimumab can cause complete hair loss in rare cases.
research Permanent Alopecia in Patients with Breast Cancer After Taxane Chemotherapy and Adjuvant Hormonal Therapy: Clinicopathologic Findings in a Cohort of 10 Patients
Some breast cancer patients developed permanent hair loss after chemotherapy and hormonal therapy, showing patterns similar to common baldness and alopecia areata.
research Localization of Varicella-Zoster Virus Nucleic Acids and Proteins in Human Skin
The research found that chickenpox virus spreads in skin through blood then to skin cells, while shingles virus moves from nerves to hair follicle areas before infecting skin cells.
research Adverse Dermatologic Effects of Cardiovascular Drug Therapy: Part III
Cardiovascular drugs can cause various skin problems, so recognizing these reactions is important.
research Targeted Elimination of Follicular Label-Retaining Cells by Photo-Induced Cell Killing Caused a Defect in Follicular Renewal in Mice
Killing specific cells in hair follicles can lead to hair growth problems in mice.
research Testosterone Down-Regulates Expression of αVβ3-Integrin, E-Cadherin, and Mucin-1 During Uterine Receptivity Period in Rats
Testosterone reduces key molecules needed for early pregnancy in rats.
research Dermoscopy in the Diagnosis of Tinea Capitis Infections in Children
Dermoscopy can help diagnose tinea capitis in children by looking for comma hairs, black dots, and broken hairs with white bands.
research Dandruff And Itching: An Epidemiologic Approach In France
About 17% of people in France have dandruff, and those with dandruff are more likely to have sensitive and itchy scalps.
research Combined Melanocytic Nevus Presenting with Scalp Alopecia Associated with Alopecia Areata: Coincidence or Causal?
A man's scalp hair loss was due to a combined melanocytic nevus and alopecia areata, suggesting a possible link between the two conditions.
research The Biphasic Regulatory Effect of Diphencyprone on Mouse Hair Growth and Its Relation to Protein Kinase C Isoforms
Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.
research The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
research Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration
Wnt ligands are crucial for hair growth and repair.
research Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle
Minoxidil boosts hair growth by increasing cell production and survival.
research Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review
No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
research Human Hair Growth Enhancement In Vitro By Green Tea Epigallocatechin-3-Gallate (EGCG)
Green tea component EGCG could potentially promote human hair growth.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
research A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression
The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
research Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect
Minoxidil boosts hair growth by activating PGHS-1.
research Dermal Papilla Cells Improve Wound Healing and Generate Hair Bud-Like Structures in Grafted Skin Substitutes Using Hair Follicle Stem Cells
Dermal papilla cells help wounds heal better and can potentially grow new hair.
research Permanent Chemotherapy-Induced Alopecia: Case Report and Review of the Literature
Some chemotherapy can cause permanent hair loss.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.