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Dr. Jorizzo questions the long-term benefits of minoxidil and tretinoin, while Dr. Olsen defends their effectiveness and stresses the need for public education on these treatments.

Psoriasis patients have immune cells that respond more strongly to signals and stimuli due to an intrinsic cellular defect.

Non-ablative radio frequency can potentially increase hair count in men with androgenetic alopecia, but some may be bothered by the smell during treatment.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Low-level Laser Therapy may help reduce inflammation, pain, and aid healing, but more research is needed to confirm its effectiveness and establish standard treatment guidelines.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Targeting colon cancer stem cells might lead to better treatment results.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Polymeric nanoparticles show promise for treating skin diseases.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Apoptosis is essential for human skin development and forming a functional epidermis.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.