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A new genetic mutation in mice causes permanent hair loss and skin wrinkling.

This study found that ISX9 may activate the Wnt/β-catenin signaling pathway and holds potential as a therapeutic agent for treating alopecia.

In this study, silver oxide-based nanoparticles were used to ionize analytes and detect specific target molecules through adduct formation with silver isotopes, facilitating signal correlation with these molecules.

This review emphasized the significance of biliary fibrosis in hepatobiliary disorders, exploring its clinical manifestations, epidemiology, and cellular factors, and provided insights into current clinical trials and strategies for managing fibrosis-related cholangiopathies.

In this study, fibroblasts treated with the small molecule peficitinib were reprogrammed into dermal papilla cell-like cells capable of inducing hair growth, offering a new strategy for hair loss treatment.

This study introduced a novel method that uses upright structured illumination microscopy and atomic force microscopy to map the mechanical properties of thick living tissue slices, revealing the intricate mechanical heterogeneity of mouse skin and effects of preservation techniques on tissue stiffness.

TEDAR is crucial for skin cell differentiation and barrier formation.

This study reports that extracts from pomegranate leaves contain bioactive compounds with antioxidant, antimicrobial, and skin-beneficial properties, suggesting their potential use in nutraceutical and cosmeceutical applications.

This study suggests that Gujian oral liquid may reduce osteoarthritis symptoms by regulating inflammation and catabolism through the TNF-α/NF-kappa B signaling pathway, as confirmed by both in vivo and in vitro experiments.

This study found that a sub-fraction of Noni fruit, FEA-3, showed hair growth-promoting effects in a rabbit model of androgenic alopecia, similar to Minoxidil.

This study establishes a robust analytical method using mass spectrometry to comprehensively identify 170 chemical compounds in Xiaoban Kangfu capsules for enhanced quality control.

This review discusses the chemical composition, potential health benefits, and extraction methods of red ginseng oil, and reports no new clinical results but emphasizes safety and proposed molecular mechanisms.

This study found that certain lncRNA gene polymorphisms in HOTAIR and MALAT1 are associated with increased susceptibility to systemic lupus erythematosus, potentially informing clinical applications.

Andrographolide from Andrographis paniculata promotes hair growth and could be a natural treatment for hair loss.

This study found that scalp melanoma often occurs in areas with androgenetic alopecia, and patients without alopecia might experience a later diagnosis due to hair coverage, leading to potentially worse outcomes.

This study identified seven new compounds from the plant Sansevieria trifasciata Prain and predicted that four of them may have better anti-alopecia activity than minoxidil through an in silico approach.

Inhibiting Bmp signaling disrupts hair growth and differentiation.

This study found that micro-niches within hair follicles create heterogeneity among stem cells and transit-amplifying cells, leading to specialized progenitors that control tissue morphogenesis and regeneration.

This study found that overexpression and knockdown of DKK4 influence genes involved in hair follicle growth and development in Angora rabbits and identified specific SNPs in DKK4 associated with wool quality, notably showing that the TT/GG haplotype combination relates to higher fibre diameters.

This study found that phytosterols extracted from moringa seed oil may act as potential anti-alopecia agents by inhibiting the 5α-reductase enzyme, with ergostadienol showing particularly high affinity and stability in in silico simulations.

This review discusses recent advances in understanding hair follicle stem cell dynamics and interactions, but it reports no new experimental findings.

This study mapped gene expression in different skin structures of dogs, finding similarities to humans that support using dogs as models for human skin diseases.

This study suggests that cultured hair follicle dermal sheath cup cells exhibit immune privilege properties, partly through the expression of PD-L1, which impacts co-cultured immune cells' behavior.

This review describes how cutaneous toxicity from kinase inhibitors, immune checkpoint inhibitors, and chemotherapeutics could potentially serve as a biomarker for anticancer treatment efficacy, but highlights the need for more extensive research to confirm this association.

In a mouse model, this study found that exposure to PM2.5 leads to significant postpartum hair loss, apparent via morphological changes and elevated markers of inflammation, apoptosis, and fibrosis, potentially exacerbated by changes in hormone receptors and stem cell populations.

A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

This review discusses the development, lineages, functions, and roles of fibroblasts in fibrosis across four organs, highlighting their capabilities in tissue repair and contributions to fibrotic disorders when aberrantly activated, but it reports no new experimental findings.

This review discusses the shared molecular and cellular processes in the early development stages of skin appendages like hair follicles, teeth, and mammary glands, reporting no new results.

This review explores the role of macrophage subsets in adult cutaneous wound healing and emphasizes their potential for therapeutic targeting, but reports no new experimental results.

This study identified key long non-coding RNAs and mRNAs involved in primary wool follicle induction in carpet wool sheep, emphasizing their roles in hair follicle development and skin processes.