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This review summarizes 25 small molecule drugs with in vitro and in vivo data for COVID-19 treatment, highlighting their structural diversity and potential to guide future antiviral discovery.

In this study, researchers identified key miRNAs and target genes involved in hair follicle development in Merino sheep, providing insights that could aid in improving sheep breeding for wool quality.

This study provides a detailed profile of bioactive polyphenols in various parts of the baobab fruit, highlighting its potential as a health-promoting food or supplement.

This mini-review details how the SOX family of transcription factors contributes to cancer immune evasion by affecting antigen presentation, impacting the tumor's immunosuppressive environment, and regulating immune checkpoints, offering insights for developing novel immunotherapy strategies.

This study suggests that phytochemicals from natural sources could be safer alternatives to conventional treatments for hair loss, as they may activate key pathways involved in hair growth.

Ultrasound can improve targeted drug delivery, making treatments more effective with fewer side effects.

In this study, researchers developed a new solution called CapilGen, showing it increased hair quantity by 35% and density by 25% in clinical trials without side effects, providing a potentially safe and effective treatment for baldness.

This study found that human induced pluripotent stem cells differentiated precisely to express certain markers during a specific window could enable successful hair follicle generation when transplanted.

In this study, perilla seed extract obtained through supercritical fluid extraction was found to promote hair follicle cell proliferation and downregulate key genes linked to androgenetic alopecia, showing potential as a natural treatment for hair loss in vitro.

RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.

This study identified ISX9 as a novel agonist of the Wnt/β‐catenin pathway, which promoted hair regrowth in mice and may offer a therapeutic approach for alopecia.

This review discusses the medicinal uses and phytochemical composition of Eclipta alba and reports no new clinical findings; the authors suggest its potential therapeutic significance due to complex interactions of its constituents.

This study reported that compounds from the root of Beta vulgaris, specifically 4-picoline and Betalain, showed potential as effective anti-hair loss treatments by demonstrating significant inhibitory activity against the enzyme 5α-reductase in a computational molecular docking study.

This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.

In this study, Gardenia florida fruit extract promoted hair growth in vitro and in vivo by enhancing hair growth-promoting gene expression and increasing hair follicle number, size, and depth in mice.

This study found that Adapalene, Diosmin, and Azelastine have potential as multi-target drugs against Onchocerca volvulus and its endosymbiont, which might offer new therapeutic options for treating river blindness, but further research is needed to confirm their effectiveness.

This study found that altering levels of SFRP1 in human dermal papilla cells affects cell function and regulates Wnt/β-catenin signaling or telomerase activity, suggesting that targeting SFRP1 could potentially offer a new approach to treat hair loss diseases.

This study establishes a robust analytical method using mass spectrometry to comprehensively identify 170 chemical compounds in Xiaoban Kangfu capsules for enhanced quality control.

In this study, silver oxide-based nanoparticles were used to ionize analytes and detect specific target molecules through adduct formation with silver isotopes, facilitating signal correlation with these molecules.

In this study, researchers used a network pharmacology approach to highlight significant interactions between compounds in rosemary (Salvia rosmarinus) and genes related to functional dyspepsia, suggesting potential pathways for developing treatments against gastrointestinal diseases.

This review reports that exosome-based therapies, coupled with nanotechnology and AI, show promise in aesthetic medicine, notably in skin rejuvenation and hair restoration, but large-scale trials and clearer regulatory frameworks are needed for effective clinical adoption.

This review highlights LTBP1 as a critical integrator in disease processes, showing its dual role in cancer progression and suppression, its pathological influence in fibrosis, and its contribution to various disorders, suggesting its potential as a biomarker and therapeutic target.

The study observed that the tumor suppressor activity of bone morphogenetic proteins in mouse skin epithelium depends on Noggin levels, inhibiting Wnt and Shh signaling pathways to prevent tumor initiation and progression.

This review discusses the chemical composition, potential health benefits, and extraction methods of red ginseng oil, and reports no new clinical results but emphasizes safety and proposed molecular mechanisms.

Andrographolide from Andrographis paniculata promotes hair growth and could be a natural treatment for hair loss.

This article discusses the development and clinical progress of PROTAC technology, particularly focusing on the New Drug Application for vepdegestrant, an estrogen receptor-targeting PROTAC, marking significant advancements in targeted protein degradation therapies.

This review examines the potential mechanisms by which stem cell-derived cell-free therapy may prevent skin aging, highlighting various molecular targets and pathways involved in regeneration, oxidative stress regulation, ECM preservation, cell activity modulation, and inflammation.

This review highlights the need for optimizing mesenchymal stromal/stem cell therapy through tailored in vitro strategies to unlock their full potential for treating specific diseases.

This review discusses platelet-rich plasma as a treatment for androgenetic alopecia and explains its mechanisms, but presents no new clinical results.

This study found that the compound (+)–Marmesin from Petroselinum crispum showed potential as an anti-alopecia agent by demonstrating better binding to androgen receptors than minoxidil, though not surpassing native ligands.