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Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.

ILK is essential for skin development, pigmentation, and healing.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

The document concludes that certain chemicals can help maintain stem cell pluripotency and that understanding cell states is crucial for tissue regeneration.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.

ILK is essential for proper hair follicle development and structure.

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.

UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.

Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.

Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.

Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.

Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

High TSPEAR levels in colorectal cancer predict worse outcomes.

High TSPEAR levels in colorectal cancer predict worse outcomes.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Beta-caryophyllene helps improve wound healing in mice, especially in females.