research Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes
The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
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research Ectodysplasin Research: Where to Next?
Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
research Viewpoint 4
Skin patterns form through molecular signals and genetic factors, affecting healing and dermatology.
research Molecular Genetic Characteristics of the Hoxc13 Gene and Association Analysis of Wool Traits
Hoxc13 gene affects wool length in Gansu alpine fine-wool sheep.
research Evolution and Function of Vitamin D
Vitamin D is essential for bone health and may reduce risks of several diseases.
research The Evolutionary Impact of Androgen Levels on Prostate Cancer in a Multi-Scale Mathematical Model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
research Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Both gene and non-gene areas of DNA evolved to make some mammals hairless.
research Molecular Basis of Androgenetic Alopecia
research Molecular Regulatory Mechanisms in Chicken Feather Follicle Morphogenesis
The document concludes that various signaling pathways and genetic factors are crucial for chicken feather development, affecting poultry quality.
research The Molecular Anatomy of Cashmere Goat Hair Follicle During Cytodifferentiation Stage
Understanding hair follicle development can help improve cashmere quality.
research Precision Dermatology: A Review of Molecular Biomarkers and Personalized Therapies
Personalized medicine in dermatology uses molecular biomarkers to improve diagnosis and treatment but needs further advancements for practical use.
research Editor's Evaluation: Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
research Molecular Mechanisms of Y Chromosome Loss and UTY Gene Activity
Loss of the Y chromosome and UTY gene activity increases cancer risk in men.
research Evolution of Hair Treatment and Care: Prospects of Nanotube-Based Formulations
Nanotube-based hair treatments could improve hair health and growth, and offer long-lasting effects.
research Evolution And Genetic Architecture Of Sex-Limited Polymorphism In Cuckoos
Female cuckoo color differences are linked to their unique genes and help avoid male harassment.
research Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages
Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.
research In Search of New Therapeutics: Molecular Aspects of the PCOS Pathophysiology - Genetics, Hormones, Metabolism and Beyond
New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
research Penetration of Different Molecular Weight Hydrolysed Keratins into Hair Fibres and Their Effects on the Physical Properties of Textured Hair
Different sizes of keratin peptides can strengthen hair, with smaller ones possibly increasing volume and larger ones repairing damage.
research An ERK-Dependent Molecular Switch Antagonizes Fibrosis and Promotes Regeneration in Spiny Mice
High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
research Chapter 4: Cytomechanics of Hair
Hair's strength and flexibility come from its protein structure and molecular interactions.
research Nerve Growth Factor and Burn Wound Healing: Update of Molecular Interactions With Skin Cells
Nerve growth factor helps improve healing time and scar quality in burn wounds.
research Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution, And Tumor-Initiating Cells
Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Platelet-Rich Plasma as a Site-Targeted Approach in Wound Healing: A Molecular Perspective
Platelet-rich plasma may improve wound healing by stimulating cell growth and blood vessel formation.
research Platelet-Rich Plasma in Dermatology: Cellular and Molecular Mechanisms of Action
PRP therapy helps skin heal and improve by promoting cell growth and repair.
research Size Polymorphisms in the Human Ultrahigh Sulfur Hair Keratin-Associated Protein 4, KAP4, Gene Family
The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.
research Ex Vivo SIM-AFM Measurements Reveal the Spatial Correlation of Stiffness and Molecular Distributions in 3D Living Tissue
Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.
research Phenotypic Heterogeneity in Human Genetic Diseases: Ultrasensitivity-Mediated Threshold Effects as a Unifying Molecular Mechanism
Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
research Deciphering Principles of Morphogenesis from Temporal and Spatial Patterns on the Integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Convergent Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.