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Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

Spironolactone plus finasteride reduces hirsutism more effectively.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Minoxidil can harm dog's heart.

Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Oral JAK inhibitors are effective and safe for treating alopecia areata but may need ongoing use to keep results.

Spironolactone might help protect against severe lung problems in COVID-19 patients.

Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Type I interferons play a key role in the development of various skin diseases.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.

β-blockers can cause skin problems like psoriasis and vitiligo, and doctors should tell patients about these risks.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.

Hedychium spicatum has medicinal properties but needs more research for scientific validation and use.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Minoxidil use during pregnancy may cause fetal harm.