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Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

RTA 408 cream protects mice from radiation skin damage.

Women with PCOS often experience anxiety, depression, and a lower quality of life.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Using psychological treatments can help manage skin conditions along with regular medical care.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Hair loss in elderly women is often caused by various factors, including hormonal changes after menopause.

Rats had lasting erectile problems after stopping a certain medication.

Topical tofacitinib may grow hair better than minoxidil by increasing VEGF and reducing inflammation.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.

Effective symptom management in IBD improves quality of life and prevents complications.

Sebaceous glands are involved in various skin disorders, some treatable with medications like finasteride and minoxidil.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Washing hair daily is better and preferred, with no negative effects.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

Hair loss may signal metabolic problems and increased risk of heart disease, suggesting people with hair loss should be checked for these issues.