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![Successful Treatment of Ulcerated Infantile Hemangioma Associated with PELVIS Syndrome Using Oral Propranolol](/images/research/dc31a458-35c5-4393-9021-09c9688ed8df/small/20287.jpg)
research Successful Treatment of Ulcerated Infantile Hemangioma Associated with PELVIS Syndrome Using Oral Propranolol
Oral propranolol successfully treated a baby's skin growth and ulceration linked to PELVIS syndrome.
![Trends in the Presence or Absence of Transaminitis and/or Leukopenia in Pediatric Patients Treated with Methotrexate for Inflammatory Skin Disease](/images/research/4947bd16-f222-4174-8978-2ef80caa1591/small/20294.jpg)
research Trends in the Presence or Absence of Transaminitis and/or Leukopenia in Pediatric Patients Treated with Methotrexate for Inflammatory Skin Disease
Most children with skin inflammation taking methotrexate had lab abnormalities, but liver issues often improved without changing the medication dose.
![Association of 5-Alpha Reductase Inhibitors and Sexual Dysfunction: A RADAR Report](/images/research/13586934-0757-4eaf-bc68-9bbcd8f19d31/small/20289.jpg)
research Association of 5-Alpha Reductase Inhibitors and Sexual Dysfunction: A RADAR Report
Using hair loss drugs finasteride and dutasteride may cause sexual side effects.
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![Efficacy of Topical Nanoemulsion (NB-002) for the Treatment of Distal Subungual Onychomycosis: A Randomized, Double-Blind, Vehicle-Controlled Trial](/images/research/a1bc9994-eac1-4d1a-8e22-e1c31b52603b/small/21974.jpg)
research Efficacy of Topical Nanoemulsion (NB-002) for the Treatment of Distal Subungual Onychomycosis: A Randomized, Double-Blind, Vehicle-Controlled Trial
NB-002 is a promising new topical treatment for fungal nail infections, showing better results than a non-medicated option.
![Crystal Structure of 17-Beta-Benzoyloxy-16-Beta-Methylpregna-4,6-Diene-3,20-Dione](/images/research/18a232e2-a020-472b-afda-81573ad73e50/small/15548.jpg)
research Crystal Structure of 17-Beta-Benzoyloxy-16-Beta-Methylpregna-4,6-Diene-3,20-Dione
A new antiandrogen compound was made and its detailed three-dimensional shape was described.
![Beyond Goosebumps: Interactions Between the Hair Follicle, the Arrector Pili Muscle, and the Sympathetic Nerve During Development and Hair Follicle Regeneration](/images/research/4f249563-7b44-4999-828f-5262af59466e/small/4289.jpg)
research Beyond Goosebumps: Interactions Between the Hair Follicle, the Arrector Pili Muscle, and the Sympathetic Nerve During Development and Hair Follicle Regeneration
Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.
![Implantation of Biocompatible Fibers for the Temporary Correction of Scalp Scars and Androgenetic Alopecia](/images/research/e3b27923-da84-44ea-8493-924b4c062d1b/small/2482.jpg)
research Implantation of Biocompatible Fibers for the Temporary Correction of Scalp Scars and Androgenetic Alopecia
Fiber implants effectively treat permanent hair loss with few complications.
![Molecular Principles of Hair Follicle Induction and Morphogenesis](/images/research/dd8d9b76-e36c-42eb-b095-f0478c36b23e/small/35678.jpg)
research Molecular Principles of Hair Follicle Induction and Morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
![Doing Well by Doing Good: The Benevolent Halo of Corporate Social Responsibility](/images/research/b8b8db54-cf16-4b7c-b3f3-00c8e92cd54a/small/21755.jpg)
research Doing Well by Doing Good: The Benevolent Halo of Corporate Social Responsibility
Corporate social responsibility can improve consumer ratings of product performance, especially when the company is seen as benevolent and consumers aren't experts on the product.
![Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia](/images/research/d57b3ea2-5b6a-4ac1-a8b2-517bd72ed1bd/small/2162.jpg)
research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
![The Neurobiology of Sexual Function](/images/research/bfa5d828-43cc-4190-a6fb-33cd059f05ff/small/15513.jpg)
research The Neurobiology of Sexual Function
Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.
![Epidemiology, Diagnosis, and Management of Hirsutism: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome Society](/images/research/688715c6-5549-41c7-81ab-79c92b995138/small/27518.jpg)
research Epidemiology, Diagnosis, and Management of Hirsutism: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome Society
Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.
![Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review](/images/research/1664adac-cd28-45a6-b16c-c3f862b795b7/small/15081.jpg)
research Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
![Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition](/images/research/9cf7c66b-3dfe-4603-a199-1096023ec3da/small/15238.jpg)
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
![Long-Term Renewal of Hair Follicles from Clonogenic Multipotent Stem Cells](/images/research/81b9a774-4800-4419-ab36-3029aa00744b/small/29506.jpg)
research Long-Term Renewal of Hair Follicles from Clonogenic Multipotent Stem Cells
Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.
![Environmental Factors and Puberty Timing: Expert Panel Research Needs](/images/research/ca7028eb-e9a7-4187-a386-dc502002a844/small/15052.jpg)
research Environmental Factors and Puberty Timing: Expert Panel Research Needs
Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.
![Androgen Therapy in Women: An Endocrine Society Clinical Practice Guideline](/images/research/d6a32ee2-37af-4439-aa23-62a12214fd60/small/15213.jpg)
research Androgen Therapy in Women: An Endocrine Society Clinical Practice Guideline
The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
![Polycystic Ovary Syndrome: Comprehensive Overview](/images/research/21903ea5-873d-4ed8-a5f2-9c487f346e4a/small/13763.jpg)
research Polycystic Ovary Syndrome: Comprehensive Overview
PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.
![Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline](/images/research/2254a31a-f7c4-4952-9e76-5180158f50f3/small/20990.jpg)
research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
![Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis](/images/research/3e93a7c2-fff4-4558-8476-b9fb9d027b06/small/13945.jpg)
research Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis
Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
![The Prevalence of Polycystic Ovary Syndrome in a Community Sample of Iranian Population: Iranian PCOS Prevalence Study](/images/research/a5a31551-379e-467e-934d-a9f46e012073/small/21013.jpg)
research The Prevalence of Polycystic Ovary Syndrome in a Community Sample of Iranian Population: Iranian PCOS Prevalence Study
About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.
![APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex](/images/research/e10f0ab5-0794-4b60-a1a0-1fb319a671a3/small/26265.jpg)
research APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex
A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
![Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches](/images/research/65396bcf-b9c6-415c-bfbf-0c1e35a7b688/small/3156.jpg)
research Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches
Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
![Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles](/images/research/4bf81027-5b72-46a2-a801-48cc9396d08a/small/28542.jpg)
research Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles
The new "differential stripping" method effectively measures how much substance gets into hair follicles.
![Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia](/images/research/06fd64bd-3af4-499e-bc89-983998bf86fb/small/2982.jpg)
research Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia
Finasteride helps hair growth but may cause sexual side effects.
![Increased Copy Number of the TERT and TERC Telomerase Subunit Genes in Cancer Cells](/images/research/e6c4adf9-c5b4-4bc2-bb61-3fae32c8ab50/small/23225.jpg)
research Increased Copy Number of the TERT and TERC Telomerase Subunit Genes in Cancer Cells
Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.